Survival beyond 10 years following heart transplantation: The Cleveland Clinic Foundation experience

V. Ozduran, M. H. Yamani, H. H. Chuang, I. Sipahi, D. J. Cook, D. Sendrey, L. Tong, R. Hobbs, G. Rincon, C. Bott-Silverman, K. James, D. O. Taylor, J. B. Young, J. Navia, M. Banbury, N. Smedira, R. C. Starling

Research output: Contribution to journalArticle

24 Scopus citations

Abstract

Background. Long-term survival after heart transplantation is a desirable although challenging goal. Methods. We analyzed clinical outcomes in the cohort of 170 patients who have undergone heart transplantation at The Cleveland Clinic Foundation and survived >10 years. Results. We found 10-year and 15-year survival rates of 54% and 41%, respectively, in these patients, but there was also a high incidence of complications, such as hypertension, renal dysfunction, transplant vasculopathy, and malignancy. Conclusions. Long-term survival following cardiac transplantation is possible although complications are frequent. Beyond 10 years, malignancy is a major cause of death.

Original languageEnglish (US)
Pages (from-to)4509-4512
Number of pages4
JournalTransplantation proceedings
Volume37
Issue number10
DOIs
StatePublished - Dec 1 2005

ASJC Scopus subject areas

  • Surgery
  • Transplantation

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    Ozduran, V., Yamani, M. H., Chuang, H. H., Sipahi, I., Cook, D. J., Sendrey, D., Tong, L., Hobbs, R., Rincon, G., Bott-Silverman, C., James, K., Taylor, D. O., Young, J. B., Navia, J., Banbury, M., Smedira, N., & Starling, R. C. (2005). Survival beyond 10 years following heart transplantation: The Cleveland Clinic Foundation experience. Transplantation proceedings, 37(10), 4509-4512. https://doi.org/10.1016/j.transproceed.2005.10.021