Survival beyond 10 years following heart transplantation: The Cleveland Clinic Foundation experience

V. Ozduran; M. H. Yamani; H. H. Chuang; I. Sipahi; D. J. Cook; D. Sendrey; L. Tong; R. Hobbs; G. Rincon; C. Bott-Silverman; K. James; D. O. Taylor; J. B. Young; J. Navia; M. Banbury; N. Smedira; R. C. Starling

doi:10.1016/j.transproceed.2005.10.021

Survival beyond 10 years following heart transplantation: The Cleveland Clinic Foundation experience

V. Ozduran, M. H. Yamani, H. H. Chuang, I. Sipahi, D. J. Cook, D. Sendrey, L. Tong, R. Hobbs, G. Rincon, C. Bott-Silverman, K. James, D. O. Taylor, J. B. Young, J. Navia, M. Banbury, N. Smedira, R. C. Starling

Cardiovascular Diseases

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

Background. Long-term survival after heart transplantation is a desirable although challenging goal. Methods. We analyzed clinical outcomes in the cohort of 170 patients who have undergone heart transplantation at The Cleveland Clinic Foundation and survived >10 years. Results. We found 10-year and 15-year survival rates of 54% and 41%, respectively, in these patients, but there was also a high incidence of complications, such as hypertension, renal dysfunction, transplant vasculopathy, and malignancy. Conclusions. Long-term survival following cardiac transplantation is possible although complications are frequent. Beyond 10 years, malignancy is a major cause of death.

Original language	English (US)
Pages (from-to)	4509-4512
Number of pages	4
Journal	Transplantation proceedings
Volume	37
Issue number	10
DOIs	https://doi.org/10.1016/j.transproceed.2005.10.021
State	Published - Dec 2005

ASJC Scopus subject areas

Surgery
Transplantation

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10.1016/j.transproceed.2005.10.021

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Ozduran, V., Yamani, M. H., Chuang, H. H., Sipahi, I., Cook, D. J., Sendrey, D., Tong, L., Hobbs, R., Rincon, G., Bott-Silverman, C., James, K., Taylor, D. O., Young, J. B., Navia, J., Banbury, M., Smedira, N., & Starling, R. C. (2005). Survival beyond 10 years following heart transplantation: The Cleveland Clinic Foundation experience. Transplantation proceedings, 37(10), 4509-4512. https://doi.org/10.1016/j.transproceed.2005.10.021

Ozduran, V, Yamani, MH, Chuang, HH, Sipahi, I, Cook, DJ, Sendrey, D, Tong, L, Hobbs, R, Rincon, G, Bott-Silverman, C, James, K, Taylor, DO, Young, JB, Navia, J, Banbury, M, Smedira, N & Starling, RC 2005, 'Survival beyond 10 years following heart transplantation: The Cleveland Clinic Foundation experience', Transplantation proceedings, vol. 37, no. 10, pp. 4509-4512. https://doi.org/10.1016/j.transproceed.2005.10.021

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title = "Survival beyond 10 years following heart transplantation: The Cleveland Clinic Foundation experience",

abstract = "Background. Long-term survival after heart transplantation is a desirable although challenging goal. Methods. We analyzed clinical outcomes in the cohort of 170 patients who have undergone heart transplantation at The Cleveland Clinic Foundation and survived >10 years. Results. We found 10-year and 15-year survival rates of 54% and 41%, respectively, in these patients, but there was also a high incidence of complications, such as hypertension, renal dysfunction, transplant vasculopathy, and malignancy. Conclusions. Long-term survival following cardiac transplantation is possible although complications are frequent. Beyond 10 years, malignancy is a major cause of death.",

author = "V. Ozduran and Yamani, {M. H.} and Chuang, {H. H.} and I. Sipahi and Cook, {D. J.} and D. Sendrey and L. Tong and R. Hobbs and G. Rincon and C. Bott-Silverman and K. James and Taylor, {D. O.} and Young, {J. B.} and J. Navia and M. Banbury and N. Smedira and Starling, {R. C.}",

year = "2005",

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doi = "10.1016/j.transproceed.2005.10.021",

language = "English (US)",

volume = "37",

pages = "4509--4512",

journal = "Transplantation proceedings",

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TY - JOUR

T1 - Survival beyond 10 years following heart transplantation

T2 - The Cleveland Clinic Foundation experience

AU - Ozduran, V.

AU - Yamani, M. H.

AU - Chuang, H. H.

AU - Sipahi, I.

AU - Cook, D. J.

AU - Sendrey, D.

AU - Tong, L.

AU - Hobbs, R.

AU - Rincon, G.

AU - Bott-Silverman, C.

AU - James, K.

AU - Taylor, D. O.

AU - Young, J. B.

AU - Navia, J.

AU - Banbury, M.

AU - Smedira, N.

AU - Starling, R. C.

PY - 2005/12

Y1 - 2005/12

N2 - Background. Long-term survival after heart transplantation is a desirable although challenging goal. Methods. We analyzed clinical outcomes in the cohort of 170 patients who have undergone heart transplantation at The Cleveland Clinic Foundation and survived >10 years. Results. We found 10-year and 15-year survival rates of 54% and 41%, respectively, in these patients, but there was also a high incidence of complications, such as hypertension, renal dysfunction, transplant vasculopathy, and malignancy. Conclusions. Long-term survival following cardiac transplantation is possible although complications are frequent. Beyond 10 years, malignancy is a major cause of death.

AB - Background. Long-term survival after heart transplantation is a desirable although challenging goal. Methods. We analyzed clinical outcomes in the cohort of 170 patients who have undergone heart transplantation at The Cleveland Clinic Foundation and survived >10 years. Results. We found 10-year and 15-year survival rates of 54% and 41%, respectively, in these patients, but there was also a high incidence of complications, such as hypertension, renal dysfunction, transplant vasculopathy, and malignancy. Conclusions. Long-term survival following cardiac transplantation is possible although complications are frequent. Beyond 10 years, malignancy is a major cause of death.

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JF - Transplantation proceedings

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Survival beyond 10 years following heart transplantation: The Cleveland Clinic Foundation experience

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