Survival associated with two sets of diagnostic criteria for congestive heart failure

Gina D. Schellenbaum, Thomas D. Rea, Susan R. Heckbert, Nicholas L. Smith, Thomas Lumley, Veronique Lee Roger, Dalane W. Kitzman, Herman A. Taylor, Daniel Levy, Bruce M. Psaty

Research output: Contribution to journalArticle

60 Citations (Scopus)

Abstract

Congestive heart failure (CHF) definitions vary across epidemiologic studies. The Framingham Heart Study criteria include CHF signs and symptoms assessed by a physician panel. In the Cardiovascular Health Study, a committee of physicians adjudicated CHF diagnoses, confirmed by signs, symptoms, clinical tests, and/or medical therapy. The authors used data from the Cardiovascular Health Study, a population-based cohort study of 5,888 elderly US adults, to compare CHF incidence and survival patterns following onset of CHF as defined by Framingham and/or Cardiovascular Health Study criteria. They constructed an inception cohort of nonfatal, hospitalized CHF patients. Of 875 participants who had qualifying CHF hospitalizations between 1989 and 2000, 54% experienced a first CHF event that fulfilled both sets of diagnostic criteria (concordant), 31% fulfilled only the Framingham criteria (Framingham only), and 15% fulfilled only the Cardiovascular Health Study criteria (Cardiovascular Health Study only). No significant survival difference was found between the Framingham-only group (hazard ratio = 0.87, 95% confidence interval: 0.71, 1.07) or the Cardiovascular Health Study-only group (hazard ratio = 0.89, 95% confidence interval: 0.68, 1.15) and the concordant group (referent). Compared with Cardiovascular Health Study central adjudication, Framingham criteria for CHF identified a larger group of participants with incident CHF, but all-cause mortality rates were similar across these diagnostic classifications.

Original languageEnglish (US)
Pages (from-to)628-635
Number of pages8
JournalAmerican Journal of Epidemiology
Volume160
Issue number7
DOIs
StatePublished - Oct 1 2004

Fingerprint

Heart Failure
Survival
Health
Signs and Symptoms
Confidence Intervals
Physicians
Epidemiologic Studies
Hospitalization
Cohort Studies
Mortality
Incidence
Population

Keywords

  • Congestive
  • Follow-up studies
  • Heart failure
  • Prognosis
  • Survival

ASJC Scopus subject areas

  • Epidemiology

Cite this

Schellenbaum, G. D., Rea, T. D., Heckbert, S. R., Smith, N. L., Lumley, T., Roger, V. L., ... Psaty, B. M. (2004). Survival associated with two sets of diagnostic criteria for congestive heart failure. American Journal of Epidemiology, 160(7), 628-635. https://doi.org/10.1093/aje/kwh268

Survival associated with two sets of diagnostic criteria for congestive heart failure. / Schellenbaum, Gina D.; Rea, Thomas D.; Heckbert, Susan R.; Smith, Nicholas L.; Lumley, Thomas; Roger, Veronique Lee; Kitzman, Dalane W.; Taylor, Herman A.; Levy, Daniel; Psaty, Bruce M.

In: American Journal of Epidemiology, Vol. 160, No. 7, 01.10.2004, p. 628-635.

Research output: Contribution to journalArticle

Schellenbaum, GD, Rea, TD, Heckbert, SR, Smith, NL, Lumley, T, Roger, VL, Kitzman, DW, Taylor, HA, Levy, D & Psaty, BM 2004, 'Survival associated with two sets of diagnostic criteria for congestive heart failure', American Journal of Epidemiology, vol. 160, no. 7, pp. 628-635. https://doi.org/10.1093/aje/kwh268
Schellenbaum, Gina D. ; Rea, Thomas D. ; Heckbert, Susan R. ; Smith, Nicholas L. ; Lumley, Thomas ; Roger, Veronique Lee ; Kitzman, Dalane W. ; Taylor, Herman A. ; Levy, Daniel ; Psaty, Bruce M. / Survival associated with two sets of diagnostic criteria for congestive heart failure. In: American Journal of Epidemiology. 2004 ; Vol. 160, No. 7. pp. 628-635.
@article{7a5d44e905bb4aa4840f77cd6d4548b7,
title = "Survival associated with two sets of diagnostic criteria for congestive heart failure",
abstract = "Congestive heart failure (CHF) definitions vary across epidemiologic studies. The Framingham Heart Study criteria include CHF signs and symptoms assessed by a physician panel. In the Cardiovascular Health Study, a committee of physicians adjudicated CHF diagnoses, confirmed by signs, symptoms, clinical tests, and/or medical therapy. The authors used data from the Cardiovascular Health Study, a population-based cohort study of 5,888 elderly US adults, to compare CHF incidence and survival patterns following onset of CHF as defined by Framingham and/or Cardiovascular Health Study criteria. They constructed an inception cohort of nonfatal, hospitalized CHF patients. Of 875 participants who had qualifying CHF hospitalizations between 1989 and 2000, 54{\%} experienced a first CHF event that fulfilled both sets of diagnostic criteria (concordant), 31{\%} fulfilled only the Framingham criteria (Framingham only), and 15{\%} fulfilled only the Cardiovascular Health Study criteria (Cardiovascular Health Study only). No significant survival difference was found between the Framingham-only group (hazard ratio = 0.87, 95{\%} confidence interval: 0.71, 1.07) or the Cardiovascular Health Study-only group (hazard ratio = 0.89, 95{\%} confidence interval: 0.68, 1.15) and the concordant group (referent). Compared with Cardiovascular Health Study central adjudication, Framingham criteria for CHF identified a larger group of participants with incident CHF, but all-cause mortality rates were similar across these diagnostic classifications.",
keywords = "Congestive, Follow-up studies, Heart failure, Prognosis, Survival",
author = "Schellenbaum, {Gina D.} and Rea, {Thomas D.} and Heckbert, {Susan R.} and Smith, {Nicholas L.} and Thomas Lumley and Roger, {Veronique Lee} and Kitzman, {Dalane W.} and Taylor, {Herman A.} and Daniel Levy and Psaty, {Bruce M.}",
year = "2004",
month = "10",
day = "1",
doi = "10.1093/aje/kwh268",
language = "English (US)",
volume = "160",
pages = "628--635",
journal = "American Journal of Epidemiology",
issn = "0002-9262",
publisher = "Oxford University Press",
number = "7",

}

TY - JOUR

T1 - Survival associated with two sets of diagnostic criteria for congestive heart failure

AU - Schellenbaum, Gina D.

AU - Rea, Thomas D.

AU - Heckbert, Susan R.

AU - Smith, Nicholas L.

AU - Lumley, Thomas

AU - Roger, Veronique Lee

AU - Kitzman, Dalane W.

AU - Taylor, Herman A.

AU - Levy, Daniel

AU - Psaty, Bruce M.

PY - 2004/10/1

Y1 - 2004/10/1

N2 - Congestive heart failure (CHF) definitions vary across epidemiologic studies. The Framingham Heart Study criteria include CHF signs and symptoms assessed by a physician panel. In the Cardiovascular Health Study, a committee of physicians adjudicated CHF diagnoses, confirmed by signs, symptoms, clinical tests, and/or medical therapy. The authors used data from the Cardiovascular Health Study, a population-based cohort study of 5,888 elderly US adults, to compare CHF incidence and survival patterns following onset of CHF as defined by Framingham and/or Cardiovascular Health Study criteria. They constructed an inception cohort of nonfatal, hospitalized CHF patients. Of 875 participants who had qualifying CHF hospitalizations between 1989 and 2000, 54% experienced a first CHF event that fulfilled both sets of diagnostic criteria (concordant), 31% fulfilled only the Framingham criteria (Framingham only), and 15% fulfilled only the Cardiovascular Health Study criteria (Cardiovascular Health Study only). No significant survival difference was found between the Framingham-only group (hazard ratio = 0.87, 95% confidence interval: 0.71, 1.07) or the Cardiovascular Health Study-only group (hazard ratio = 0.89, 95% confidence interval: 0.68, 1.15) and the concordant group (referent). Compared with Cardiovascular Health Study central adjudication, Framingham criteria for CHF identified a larger group of participants with incident CHF, but all-cause mortality rates were similar across these diagnostic classifications.

AB - Congestive heart failure (CHF) definitions vary across epidemiologic studies. The Framingham Heart Study criteria include CHF signs and symptoms assessed by a physician panel. In the Cardiovascular Health Study, a committee of physicians adjudicated CHF diagnoses, confirmed by signs, symptoms, clinical tests, and/or medical therapy. The authors used data from the Cardiovascular Health Study, a population-based cohort study of 5,888 elderly US adults, to compare CHF incidence and survival patterns following onset of CHF as defined by Framingham and/or Cardiovascular Health Study criteria. They constructed an inception cohort of nonfatal, hospitalized CHF patients. Of 875 participants who had qualifying CHF hospitalizations between 1989 and 2000, 54% experienced a first CHF event that fulfilled both sets of diagnostic criteria (concordant), 31% fulfilled only the Framingham criteria (Framingham only), and 15% fulfilled only the Cardiovascular Health Study criteria (Cardiovascular Health Study only). No significant survival difference was found between the Framingham-only group (hazard ratio = 0.87, 95% confidence interval: 0.71, 1.07) or the Cardiovascular Health Study-only group (hazard ratio = 0.89, 95% confidence interval: 0.68, 1.15) and the concordant group (referent). Compared with Cardiovascular Health Study central adjudication, Framingham criteria for CHF identified a larger group of participants with incident CHF, but all-cause mortality rates were similar across these diagnostic classifications.

KW - Congestive

KW - Follow-up studies

KW - Heart failure

KW - Prognosis

KW - Survival

UR - http://www.scopus.com/inward/record.url?scp=4644234509&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=4644234509&partnerID=8YFLogxK

U2 - 10.1093/aje/kwh268

DO - 10.1093/aje/kwh268

M3 - Article

C2 - 15383406

AN - SCOPUS:4644234509

VL - 160

SP - 628

EP - 635

JO - American Journal of Epidemiology

JF - American Journal of Epidemiology

SN - 0002-9262

IS - 7

ER -