TY - JOUR
T1 - Surgical vs percutaneous radiofrequency ablation for hepatocellular carcinoma in dangerous locations
AU - Huang, Ji Wei
AU - Hernandez-Alejandro, Roberto
AU - Croome, Kristopher P.
AU - Yan, Lu Nan
AU - Wu, Hong
AU - Chen, Zhe Yu
AU - Prasoon, Pankaj
AU - Zeng, Yong
PY - 2011/1/7
Y1 - 2011/1/7
N2 - AIM: To compare the long-term outcome of percutaneous vs surgical radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC) in dangerous locations. METHODS: One hundred and sixty-two patients with HCC in dangerous locations treated with percutaneous or surgical RFA were enrolled in this study. The patients were divided into percutaneous RFA group and surgical RFA group. After the patients were regularly followed up for a long time, their curative rate, hospital stay time, postoperative complications and 5-year local tumor progression were compared and analyzed. RESULTS: No significant difference was observed in curative rate between the two groups (91.3% vs 96.8%, P = 0.841). The hospital stay time was longer and more analgesics were required while the incidence of bile duct injury and RFA-related hemorrhage was lower in surgical RFA group than in percutaneous RFA group (P < 0.05). The local progression rate of HCC in dangerous locations was significantly lower in surgical RFA group than in percutaneous RFA group (P = 0.05). The relative risk of local tumor progression was 14.315 in percutaneous RFA group. CONCLUSION: The incidence of severe postoperative complications and local tumor progression is lower after surgical RFA than after percutaneous RFA.
AB - AIM: To compare the long-term outcome of percutaneous vs surgical radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC) in dangerous locations. METHODS: One hundred and sixty-two patients with HCC in dangerous locations treated with percutaneous or surgical RFA were enrolled in this study. The patients were divided into percutaneous RFA group and surgical RFA group. After the patients were regularly followed up for a long time, their curative rate, hospital stay time, postoperative complications and 5-year local tumor progression were compared and analyzed. RESULTS: No significant difference was observed in curative rate between the two groups (91.3% vs 96.8%, P = 0.841). The hospital stay time was longer and more analgesics were required while the incidence of bile duct injury and RFA-related hemorrhage was lower in surgical RFA group than in percutaneous RFA group (P < 0.05). The local progression rate of HCC in dangerous locations was significantly lower in surgical RFA group than in percutaneous RFA group (P = 0.05). The relative risk of local tumor progression was 14.315 in percutaneous RFA group. CONCLUSION: The incidence of severe postoperative complications and local tumor progression is lower after surgical RFA than after percutaneous RFA.
KW - Hepatocellular carcinoma
KW - Liver cirrhosis
KW - Local therapy
KW - Radiofrequency ablation
KW - Recurrence
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U2 - 10.3748/wjg.v17.i1.123
DO - 10.3748/wjg.v17.i1.123
M3 - Article
C2 - 21218093
AN - SCOPUS:78651516118
SN - 1007-9327
VL - 17
SP - 123
EP - 129
JO - World journal of gastroenterology
JF - World journal of gastroenterology
IS - 1
ER -