Surgical vs percutaneous radiofrequency ablation for hepatocellular carcinoma in dangerous locations

Ji Wei Huang, Roberto Hernandez-Alejandro, Kristopher P. Croome, Lu Nan Yan, Hong Wu, Zhe Yu Chen, Pankaj Prasoon, Yong Zeng

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

AIM: To compare the long-term outcome of percutaneous vs surgical radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC) in dangerous locations. METHODS: One hundred and sixty-two patients with HCC in dangerous locations treated with percutaneous or surgical RFA were enrolled in this study. The patients were divided into percutaneous RFA group and surgical RFA group. After the patients were regularly followed up for a long time, their curative rate, hospital stay time, postoperative complications and 5-year local tumor progression were compared and analyzed. RESULTS: No significant difference was observed in curative rate between the two groups (91.3% vs 96.8%, P = 0.841). The hospital stay time was longer and more analgesics were required while the incidence of bile duct injury and RFA-related hemorrhage was lower in surgical RFA group than in percutaneous RFA group (P < 0.05). The local progression rate of HCC in dangerous locations was significantly lower in surgical RFA group than in percutaneous RFA group (P = 0.05). The relative risk of local tumor progression was 14.315 in percutaneous RFA group. CONCLUSION: The incidence of severe postoperative complications and local tumor progression is lower after surgical RFA than after percutaneous RFA.

Original languageEnglish (US)
Pages (from-to)123-129
Number of pages7
JournalWorld journal of gastroenterology
Volume17
Issue number1
DOIs
StatePublished - Jan 7 2011

Keywords

  • Hepatocellular carcinoma
  • Liver cirrhosis
  • Local therapy
  • Radiofrequency ablation
  • Recurrence

ASJC Scopus subject areas

  • Gastroenterology

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