Surgical management of tumors invading the aorta and major arterial structures

Susanne G. Carpenter, William M. Stone, Thomas C. Bower, Richard J. Fowl, Samuel R. Money

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Background: This study investigates surgical management of tumors arising from or involving the aorta and major arterial structures. Methods: A retrospective single institutional review was conducted of patients undergoing arterial resection for tumors involving the aorta or major arterial structures between January 1992 and May 2009 at a tertiary care center. Patients with tumors abutting arteries without necessitating resection and those involving only venous structures were excluded. Patients were analyzed in groups by vessel involvement: aorta, carotid, external/common iliac, internal iliac, superficial femoral, and miscellaneous. Results: Sixty patients were identified and included for review. The iliac arteries were most often resected, and sarcomatous pathology was most common (37 patients, 62%). Twelve patients underwent aortic resection, with eight (67%) of these undergoing graft reconstruction, one (8%) graft patch, and two (17%) primary repair. None of the 17 patients undergoing internal iliac resection underwent reconstruction, whereas the majority of patients in all other groups underwent reconstruction. Thirty-day mortality (TDM) was 0% in all groups, except the aortic (2/12, 17% TDM), and internal iliac arteries (1/17, 6% TDM). Estimated blood loss varied widely and was not significantly different between vessel groups (p = 0.280). Overall, 44 of 60 (73%) patients had negative margins. Fourteen patients (23%) returned to the operating room, most for wound infection or dehiscence. Mean follow-up was 20.25 months (range: 0.5-122.0 months, SD: 23 months). Forty patients were followed up for more than 1 year. Thus, with an overall median follow-up of 12.25 months, overall survival was 60% with disease-free survival of 40%. Conclusions: Resection of tumors involving the aorta and major arterial structures provides a reasonable option for treatment, but with significant perioperative morbidity. In selected patients, this aggressive intervention should be considered.

Original languageEnglish (US)
Pages (from-to)1026-1035
Number of pages10
JournalAnnals of Vascular Surgery
Volume25
Issue number8
DOIs
StatePublished - Nov 2011

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Aorta
Neoplasms
Iliac Artery
Mortality
Transplants
Wound Infection
Operating Rooms
Thigh
Tertiary Care Centers
Disease-Free Survival
Arteries
Pathology
Morbidity
Survival

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Cite this

Carpenter, S. G., Stone, W. M., Bower, T. C., Fowl, R. J., & Money, S. R. (2011). Surgical management of tumors invading the aorta and major arterial structures. Annals of Vascular Surgery, 25(8), 1026-1035. https://doi.org/10.1016/j.avsg.2011.05.005

Surgical management of tumors invading the aorta and major arterial structures. / Carpenter, Susanne G.; Stone, William M.; Bower, Thomas C.; Fowl, Richard J.; Money, Samuel R.

In: Annals of Vascular Surgery, Vol. 25, No. 8, 11.2011, p. 1026-1035.

Research output: Contribution to journalArticle

Carpenter, SG, Stone, WM, Bower, TC, Fowl, RJ & Money, SR 2011, 'Surgical management of tumors invading the aorta and major arterial structures', Annals of Vascular Surgery, vol. 25, no. 8, pp. 1026-1035. https://doi.org/10.1016/j.avsg.2011.05.005
Carpenter, Susanne G. ; Stone, William M. ; Bower, Thomas C. ; Fowl, Richard J. ; Money, Samuel R. / Surgical management of tumors invading the aorta and major arterial structures. In: Annals of Vascular Surgery. 2011 ; Vol. 25, No. 8. pp. 1026-1035.
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