Surgical management of lung cancer

Sandra C. Tomaszek, Dennis A. Wigle

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

Lung cancer continues to be the most frequent cancer-related cause of death in the United States and throughout the world. Surgical resection is currently the most effective treatment in early-stage non-small-cell lung cancer, and historically the only treatment approach achieving significant cure rates. In advanced disease, therapeutic approaches involving chemotherapy and/or radiation therapy are utilized to improve prognosis, either as part of a neoadjuvant treatment approach followed by surgical resection or as definitive treatment alone. The role of surgery in locally advanced or metastatic non-small-cell lung cancer remains controversial, with more studies required to further refine the application of modern surgical techniques. For any treatment approach, thorough preoperative staging as well as careful patient selection are essential to assess the benefits and risks involved for the patient. Surgical management of early-stage non-small-cell lung cancer and its role in more advanced disease are discussed in this review.

Original languageEnglish (US)
Pages (from-to)69-77
Number of pages9
JournalSeminars in Respiratory and Critical Care Medicine
Volume32
Issue number1
DOIs
StatePublished - Apr 22 2011

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Keywords

  • Lung cancer
  • surgery
  • treatment

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine

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