TY - JOUR
T1 - Surgical correction of childhood intermittent exotropia and the risk of developing mental illness
AU - Kilgore, Khin P.
AU - Barraza, Román A.
AU - Hodge, David O.
AU - Mckenzie, Jeff A.
AU - Mohney, Brian G.
N1 - Funding Information:
All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest and none were reported. Supported in part by an unrestricted grant from Research to Prevent Blindness , Inc, New York, New York, and made possible by Grant AG034676 from the National Institute of Arthritis and Musculoskeletal and Skin Diseases , National Institutes of Health , Bethesda, Maryland, to the Rochester Epidemiology Project. Involved in Design and conduct of study (B.G.M., J.A.M.); Collection of data (J.A.M.); Management, analysis, and interpretation of data (K.P.K., R.A.B., D.O.H., J.A.M., B.G.M.); and Preparation, review, and approval of manuscript (B.G.M., D.O.H., K.P.K.).
Publisher Copyright:
© 2014 by Elsevier All rights reserved.
PY - 2014
Y1 - 2014
N2 - PURPOSE: To assess whether successful surgical intervention for intermittent exotropia, or the timing of intervention, has any effect on the development of mental illness. DESIGN: Retrospective, observational case series. METHODS: All patients (<19 years of age) diagnosed with intermittent exotropia in Olmsted County, Minnesota, from January 1, 1975, through December 31, 1994, were reviewed retrospectively. Potential cases were identified using the resources of the Rochester Epidemiology Project, a medical records database designed to capture data on any patient-physician encounter in Olmsted County, Minnesota. The main outcome measures were the occurrence and severity of mental illness among those who underwent strabismus surgery compared with those who did not. RESULTS: Ninety-six (52%) of the 184 children identified were diagnosed with a mental illness at a mean age of 23.3 years (range, 6 to 41 years). Thirty-five (36%) of the 96 children in whom mental illness developed underwent strabismus surgery. Success at surgery (<10 prism diopters) was not associated with a decreased occurrence of mental illness (P [ .30). Of the 88 patients in whom mental illness did not develop, strabismus surgery was not more commonly performed (P[.54), norwas it performed at a younger age (P[1.0),when comparedwith the 96 patients in whom mental illness developed later. CONCLUSIONS: Strabismus surgery for children with intermittent exotropia, regardless of success or age at surgery, did not alter the development of mental illness by early adulthood.
AB - PURPOSE: To assess whether successful surgical intervention for intermittent exotropia, or the timing of intervention, has any effect on the development of mental illness. DESIGN: Retrospective, observational case series. METHODS: All patients (<19 years of age) diagnosed with intermittent exotropia in Olmsted County, Minnesota, from January 1, 1975, through December 31, 1994, were reviewed retrospectively. Potential cases were identified using the resources of the Rochester Epidemiology Project, a medical records database designed to capture data on any patient-physician encounter in Olmsted County, Minnesota. The main outcome measures were the occurrence and severity of mental illness among those who underwent strabismus surgery compared with those who did not. RESULTS: Ninety-six (52%) of the 184 children identified were diagnosed with a mental illness at a mean age of 23.3 years (range, 6 to 41 years). Thirty-five (36%) of the 96 children in whom mental illness developed underwent strabismus surgery. Success at surgery (<10 prism diopters) was not associated with a decreased occurrence of mental illness (P [ .30). Of the 88 patients in whom mental illness did not develop, strabismus surgery was not more commonly performed (P[.54), norwas it performed at a younger age (P[1.0),when comparedwith the 96 patients in whom mental illness developed later. CONCLUSIONS: Strabismus surgery for children with intermittent exotropia, regardless of success or age at surgery, did not alter the development of mental illness by early adulthood.
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U2 - 10.1016/j.ajo.2014.06.008
DO - 10.1016/j.ajo.2014.06.008
M3 - Article
C2 - 24954680
AN - SCOPUS:84908550265
VL - 158
SP - 788-792.e1
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
SN - 0002-9394
IS - 4
ER -