Surgery for focal epilepsy in the older patient

Gregory D. Cascino, Frank W. Sharbrough, Kathryn A. Hirschorn, W. Richard Marsh

Research output: Contribution to journalArticlepeer-review

33 Scopus citations

Abstract

Eight of the 237 patients who received a surgical procedure for intractable partial epilepsy at the Mayo Clinic during a 3-year period were 50 years of age or older. All patients had disabling partial seizures of several years in duration that were refractory to anti epileptic drug medication. A neuroimaging-identified epileptogenic lesion prompted referral for surgical treatment in three patients. The only clinically significant morbidity associated with surgery in the eight patients was a transient exacerbation of an aphasia in a patient who underwent a left frontal corticectomy. All eight patients had a favorable seizure outcome, and three patients postoperatively are seizure free. Epilepsy surgery may be an appropriate alternate therapy for select patients in the sixth decade of life or older with medically refractory partial seizures.

Original languageEnglish (US)
Pages (from-to)1415-1417
Number of pages3
JournalNeurology
Volume41
Issue number9
DOIs
StatePublished - Sep 1991

ASJC Scopus subject areas

  • Clinical Neurology

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