Suppressive Therapy with Levothyroxine for Solitary Thyroid Nodules

Stephen J. Gordon; Julio C. Pita; Nelson B. Watts; Craig B. Wexler; Gary M. Pepper; Rachelle N. Bitton; Bruce S. Schneider; Joel I. Hamburger; Chiara Galli; Francesca Calasso; Giorgio Cantù; Luigi Carini; Paolo Rumi; Giovanni Segalini; Hossein Gharib; E. Meredith James; J. William Charboneau; James M. Naessens; Kenneth P. Offord; Colum A. Gorman

doi:10.1056/NEJM198712243172611

Suppressive Therapy with Levothyroxine for Solitary Thyroid Nodules

Stephen J. Gordon, Julio C. Pita, Nelson B. Watts, Craig B. Wexler, Gary M. Pepper, Rachelle N. Bitton, Bruce S. Schneider, Joel I. Hamburger, Chiara Galli, Francesca Calasso, Giorgio Cantù, Luigi Carini, Paolo Rumi, Giovanni Segalini, Hossein Gharib, E. Meredith James, J. William Charboneau, James M. Naessens, Kenneth P. Offord, Colum A. Gorman

Quantitative Health Sciences

Research output: Contribution to journal › Letter › peer-review

7 Scopus citations

Abstract

To the Editor: The documentation by Gharib et al. (July 9 issue)* of the absence of change in thyroid nodules treated with levothyroxine over a six-month period comes as no surprise. It has been my distinct impression that in approximately 20 to 25 percent of patients, cold thyroid nodules suppressed with levothyroxine will show some shrinkage, but usually this is not apparent for one to two years and, in general, no change can be discerned at six months. I hope therefore that the authors will continue their study for several years to document whether this clinical impression of mine, and.

Original language	English (US)
Pages (from-to)	1663-1665
Number of pages	3
Journal	New England Journal of Medicine
Volume	317
Issue number	26
DOIs	https://doi.org/10.1056/NEJM198712243172611
State	Published - Dec 24 1987

ASJC Scopus subject areas

Medicine(all)

Access to Document

10.1056/NEJM198712243172611

Cite this

Gordon, S. J., Pita, J. C., Watts, N. B., Wexler, C. B., Pepper, G. M., Bitton, R. N., Schneider, B. S., Hamburger, J. I., Galli, C., Calasso, F., Cantù, G., Carini, L., Rumi, P., Segalini, G., Gharib, H., James, E. M., Charboneau, J. W., Naessens, J. M., Offord, K. P., & Gorman, C. A. (1987). Suppressive Therapy with Levothyroxine for Solitary Thyroid Nodules. New England Journal of Medicine, 317(26), 1663-1665. https://doi.org/10.1056/NEJM198712243172611

Gordon, SJ, Pita, JC, Watts, NB, Wexler, CB, Pepper, GM, Bitton, RN, Schneider, BS, Hamburger, JI, Galli, C, Calasso, F, Cantù, G, Carini, L, Rumi, P, Segalini, G, Gharib, H, James, EM, Charboneau, JW, Naessens, JM, Offord, KP & Gorman, CA 1987, 'Suppressive Therapy with Levothyroxine for Solitary Thyroid Nodules', New England Journal of Medicine, vol. 317, no. 26, pp. 1663-1665. https://doi.org/10.1056/NEJM198712243172611

@article{de8cc992598742f095669eaa6c0b88f0,

title = "Suppressive Therapy with Levothyroxine for Solitary Thyroid Nodules",

abstract = "To the Editor: The documentation by Gharib et al. (July 9 issue)* of the absence of change in thyroid nodules treated with levothyroxine over a six-month period comes as no surprise. It has been my distinct impression that in approximately 20 to 25 percent of patients, cold thyroid nodules suppressed with levothyroxine will show some shrinkage, but usually this is not apparent for one to two years and, in general, no change can be discerned at six months. I hope therefore that the authors will continue their study for several years to document whether this clinical impression of mine, and.",

author = "Gordon, {Stephen J.} and Pita, {Julio C.} and Watts, {Nelson B.} and Wexler, {Craig B.} and Pepper, {Gary M.} and Bitton, {Rachelle N.} and Schneider, {Bruce S.} and Hamburger, {Joel I.} and Chiara Galli and Francesca Calasso and Giorgio Cant{\`u} and Luigi Carini and Paolo Rumi and Giovanni Segalini and Hossein Gharib and James, {E. Meredith} and Charboneau, {J. William} and Naessens, {James M.} and Offord, {Kenneth P.} and Gorman, {Colum A.}",

year = "1987",

month = dec,

day = "24",

doi = "10.1056/NEJM198712243172611",

language = "English (US)",

volume = "317",

pages = "1663--1665",

journal = "New England Journal of Medicine",

issn = "1533-4406",

publisher = "Massachussetts Medical Society",

number = "26",

}

TY - JOUR

T1 - Suppressive Therapy with Levothyroxine for Solitary Thyroid Nodules

AU - Gordon, Stephen J.

AU - Pita, Julio C.

AU - Watts, Nelson B.

AU - Wexler, Craig B.

AU - Pepper, Gary M.

AU - Bitton, Rachelle N.

AU - Schneider, Bruce S.

AU - Hamburger, Joel I.

AU - Galli, Chiara

AU - Calasso, Francesca

AU - Cantù, Giorgio

AU - Carini, Luigi

AU - Rumi, Paolo

AU - Segalini, Giovanni

AU - Gharib, Hossein

AU - James, E. Meredith

AU - Charboneau, J. William

AU - Naessens, James M.

AU - Offord, Kenneth P.

AU - Gorman, Colum A.

PY - 1987/12/24

Y1 - 1987/12/24

N2 - To the Editor: The documentation by Gharib et al. (July 9 issue)* of the absence of change in thyroid nodules treated with levothyroxine over a six-month period comes as no surprise. It has been my distinct impression that in approximately 20 to 25 percent of patients, cold thyroid nodules suppressed with levothyroxine will show some shrinkage, but usually this is not apparent for one to two years and, in general, no change can be discerned at six months. I hope therefore that the authors will continue their study for several years to document whether this clinical impression of mine, and.

AB - To the Editor: The documentation by Gharib et al. (July 9 issue)* of the absence of change in thyroid nodules treated with levothyroxine over a six-month period comes as no surprise. It has been my distinct impression that in approximately 20 to 25 percent of patients, cold thyroid nodules suppressed with levothyroxine will show some shrinkage, but usually this is not apparent for one to two years and, in general, no change can be discerned at six months. I hope therefore that the authors will continue their study for several years to document whether this clinical impression of mine, and.

UR - http://www.scopus.com/inward/record.url?scp=0023491217&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023491217&partnerID=8YFLogxK

U2 - 10.1056/NEJM198712243172611

DO - 10.1056/NEJM198712243172611

M3 - Letter

C2 - 3683505

AN - SCOPUS:0023491217

SN - 1533-4406

VL - 317

SP - 1663

EP - 1665

JO - New England Journal of Medicine

JF - New England Journal of Medicine

IS - 26

ER -

Suppressive Therapy with Levothyroxine for Solitary Thyroid Nodules

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this