Sulthiame Therapy for Continuous Spike and Wave in Slow-Wave Sleep

Elaine C Wirrell, Alice Wen Chi Ho, Lorie Hamiwka

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

Corticosteroids are often considered as the first therapeutic choice in children with continuous spike and wave in slow-wave sleep on electroencephalogram; however, they are associated with significant adverse effects. "Idiopathic" forms of continuous spike and wave in slow-wave sleep may represent the severe end of the spectrum of benign rolandic epilepsy of childhood. This report describes a 5-year-old male with language delay who presented with a single focal-onset, nocturnal seizure and had continuous spike and wave in slow-wave sleep on electroencephalography. After 1 month of sulthiame therapy, his electroencephalographic abnormality had resolved, and his language development improved.

Original languageEnglish (US)
Pages (from-to)204-208
Number of pages5
JournalPediatric Neurology
Volume35
Issue number3
DOIs
StatePublished - Sep 2006
Externally publishedYes

Fingerprint

Sleep
Electroencephalography
Rolandic Epilepsy
Language Development Disorders
Language Development
Adrenal Cortex Hormones
Seizures
Therapeutics
sulthiame

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health
  • Developmental Neuroscience
  • Neurology

Cite this

Sulthiame Therapy for Continuous Spike and Wave in Slow-Wave Sleep. / Wirrell, Elaine C; Ho, Alice Wen Chi; Hamiwka, Lorie.

In: Pediatric Neurology, Vol. 35, No. 3, 09.2006, p. 204-208.

Research output: Contribution to journalArticle

Wirrell, Elaine C ; Ho, Alice Wen Chi ; Hamiwka, Lorie. / Sulthiame Therapy for Continuous Spike and Wave in Slow-Wave Sleep. In: Pediatric Neurology. 2006 ; Vol. 35, No. 3. pp. 204-208.
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