Sulthiame Therapy for Continuous Spike and Wave in Slow-Wave Sleep

Elaine Wirrell, Alice Wen Chi Ho, Lorie Hamiwka

Research output: Contribution to journalArticle

33 Scopus citations

Abstract

Corticosteroids are often considered as the first therapeutic choice in children with continuous spike and wave in slow-wave sleep on electroencephalogram; however, they are associated with significant adverse effects. "Idiopathic" forms of continuous spike and wave in slow-wave sleep may represent the severe end of the spectrum of benign rolandic epilepsy of childhood. This report describes a 5-year-old male with language delay who presented with a single focal-onset, nocturnal seizure and had continuous spike and wave in slow-wave sleep on electroencephalography. After 1 month of sulthiame therapy, his electroencephalographic abnormality had resolved, and his language development improved.

Original languageEnglish (US)
Pages (from-to)204-208
Number of pages5
JournalPediatric Neurology
Volume35
Issue number3
DOIs
StatePublished - Sep 1 2006

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Neurology
  • Developmental Neuroscience
  • Clinical Neurology

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