Successful treatment with voriconazole of fungal cerebral abscess due to Cladophialophora bantiana

Mark K. Lyons, Janis E. Blair, Kevin O. Leslie

Research output: Contribution to journalArticlepeer-review

55 Scopus citations

Abstract

We report the first successfully treated case of Cladophialophora bantiana cerebral abscess with the relatively new antifungal agent voriconazole. Infection with this organism is often fatal. A 64-year-old man presented to our institution with progressive neurologic symptoms due to a brain abscess. A stereotactic brain biopsy confirmed the pathogen as C. bantiana. We discuss the successful treatment of this patient, and review the pharmacological actions of voriconazole and the literature on the treatment of this organism. Previously considered a rare cause of cerebral abscess, C. bantiana fungal infections have become more common in recent years. Aggressive and continuous treatment with voriconazole may offer an improved chance of survival in these patients.

Original languageEnglish (US)
Pages (from-to)532-534
Number of pages3
JournalClinical Neurology and Neurosurgery
Volume107
Issue number6
DOIs
StatePublished - Oct 1 2005

Keywords

  • Abscess
  • Brain
  • Cladophialophora bantiana
  • Fungus
  • Voriconazole

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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