Successful treatment of a mycophenolate mofetil-refractory proliferative lupus nephritis with Belimumab in a 19-year-old woman

E. E. Fließer, P. Korsten, M. J. Koziolek, T. B. Niewold, D. Patschan, G. A. Müller, S. A. Patschan

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

We report the case of a 19-year-old woman with progressive proliferative lupus nephritis (LN) class III after induction and maintenance therapy with mycophenolate mofetil (MMF). Despite a satisfying clinical improvement proteinuria progressed under this medication. We treated the patient with additional belimumab after discussing other options. Following treatment with belimumab, proteinuria rapidly improved to almost normal levels and clinical remission lasted. Belimumab might hold promise for this indication.

Original languageEnglish (US)
Pages (from-to)1523-1525
Number of pages3
JournalLupus
Volume22
Issue number14
DOIs
StatePublished - Dec 1 2013

Keywords

  • Proliferative lupus nephritis
  • belimumab
  • mycophenolate mofetil
  • systemic lupus erythematosus

ASJC Scopus subject areas

  • Rheumatology

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    Fließer, E. E., Korsten, P., Koziolek, M. J., Niewold, T. B., Patschan, D., Müller, G. A., & Patschan, S. A. (2013). Successful treatment of a mycophenolate mofetil-refractory proliferative lupus nephritis with Belimumab in a 19-year-old woman. Lupus, 22(14), 1523-1525. https://doi.org/10.1177/0961203313504145