Successful Renal Transplantation in a Patient With Systemic Sarcoidosis and Renal Failure Due to Focal Glomerulosclerosis

Albert G. Hakaim, Magda M. Stilmant, James Kauffman, Gunther Schmitt, Piyush Joshi, Gennaro Carpinito, Sang I. Cho

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

In 1987, a patient presented with pulmonary sarcoidosis and progressive renal failure. Percutaneous renal biopsy showed focal glomerular sclerosis (FGS). Over the subsequent 4-year period, her renal failure progressed to require hemodialysis. During this time, her pulmonary sarcoidosis was treated with daily corticosteroid therapy and she remained in clinical remission. The patient received a one-haplotype-identical living-related renal transplant from her mother. The patient is now 25 months posttransplant with a serum creatinine of 106 µol/L (1.2 mg/dL). Her sarcoidosis continues to be in clinical remission. In this report, we review the rare association of a primary glomerular lesion causing renal failure in patients with sarcoidosis. In addition, we detail the first successful renal transplant in such a patient.

Original languageEnglish (US)
Pages (from-to)493-495
Number of pages3
JournalAmerican Journal of Kidney Diseases
Volume19
Issue number5
DOIs
StatePublished - Jan 1 1992

Keywords

  • Renal transplantation
  • focal glomerulosclerosis
  • sarcoidosis

ASJC Scopus subject areas

  • Nephrology

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