Substances moved by axonal transport and released by nerve stimulation have an innervation-like effect on muscle

S. G. Younkin; R. S. Brett; B. Davey; L. H. Younkin

doi:10.1126/science.78522

Substances moved by axonal transport and released by nerve stimulation have an innervation-like effect on muscle

S. G. Younkin, R. S. Brett, B. Davey, L. H. Younkin

Neuroscience

Research output: Contribution to journal › Article › peer-review

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Abstract

Substances which have an innervation-like effect on the cholinesterase activity of organ-cultured rat extensor digitorum longus muscles are moved in nerve by axonal transport, are released from nerve by stimulation, and are present in innervated muscle but apparently absent from denervated muscle. Substances which increase the acetylcholine sensitivity of cultured muscles behave similarly.

Original language	English (US)
Pages (from-to)	1292-1295
Number of pages	4
Journal	Science
Volume	200
Issue number	4347
DOIs	https://doi.org/10.1126/science.78522
State	Published - 1978

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title = "Substances moved by axonal transport and released by nerve stimulation have an innervation-like effect on muscle",

abstract = "Substances which have an innervation-like effect on the cholinesterase activity of organ-cultured rat extensor digitorum longus muscles are moved in nerve by axonal transport, are released from nerve by stimulation, and are present in innervated muscle but apparently absent from denervated muscle. Substances which increase the acetylcholine sensitivity of cultured muscles behave similarly.",

author = "Younkin, {S. G.} and Brett, {R. S.} and B. Davey and Younkin, {L. H.}",

year = "1978",

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AU - Brett, R. S.

AU - Davey, B.

AU - Younkin, L. H.

PY - 1978

Y1 - 1978

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AB - Substances which have an innervation-like effect on the cholinesterase activity of organ-cultured rat extensor digitorum longus muscles are moved in nerve by axonal transport, are released from nerve by stimulation, and are present in innervated muscle but apparently absent from denervated muscle. Substances which increase the acetylcholine sensitivity of cultured muscles behave similarly.

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Substances moved by axonal transport and released by nerve stimulation have an innervation-like effect on muscle

Abstract

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