Subparaneurial ganglion cysts of the fibular and tibial nerves: A new variant of intraneural ganglion cysts

Nikhil K. Prasad, Nicholas M. Desy, B. Matthew Howe, Kimberly K. Amrami, Robert J. Spinner

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Over the last decade, the mechanism of formation of intraneural ganglion cysts has been established through a meticulous review of clinical findings and correlation with patterns produced on magnetic resonance imaging (MRI). Pathognomonic imaging patterns distinguish these rare lesions from the more common extraneural variants in almost all cases. In this report, we present a new pattern of cyst occurrence in the subparaneurial compartment of the nerve and provide potential anatomic explanations for its pathogenesis. Using an anatomic framework of connective tissue compartments of the nerve, we reviewed 63 (56 fibular and seven tibial) intraneural ganglion cysts in the knee region evaluated at our institution and all reports with MRI in the world's literature for evidence of cyst occurrence in the subparaneurial compartment. We identified six cases (five in the common fibular nerve and one in the tibial nerve) at our institution that had MR evidence of cyst in the subparaneurial compartment with a new complex lobulated pattern. All cases had articular branch connections to the superior tibiofibular joint, which at operation were resected along with the joints. Follow-up revealed complete recovery in all instances and no clinical or radiological signs of recurrence. Three cases out of 80 in the literature exhibited the new complex lobulated MRI pattern. We present a new pattern of intraneural ganglion cyst occurrence in a potential space that surrounds peripheral nerves- the subparaneurial compartment. We believe that the unifying articular theory applies to the pathogenesis and management of these rare variants. Clin. Anat. 29:530-537, 2016.

Original languageEnglish (US)
Pages (from-to)530-537
Number of pages8
JournalClinical Anatomy
Volume29
Issue number4
DOIs
StatePublished - May 1 2016

Fingerprint

Ganglion Cysts
Tibial Nerve
Peroneal Nerve
Cysts
Joints
Magnetic Resonance Imaging
Knee Joint
Peripheral Nerves
Connective Tissue
Knee
Recurrence

Keywords

  • fibular nerve
  • ganglion cysts
  • knee joint
  • MRI
  • tibial nerve

ASJC Scopus subject areas

  • Anatomy
  • Histology

Cite this

Subparaneurial ganglion cysts of the fibular and tibial nerves : A new variant of intraneural ganglion cysts. / Prasad, Nikhil K.; Desy, Nicholas M.; Howe, B. Matthew; Amrami, Kimberly K.; Spinner, Robert J.

In: Clinical Anatomy, Vol. 29, No. 4, 01.05.2016, p. 530-537.

Research output: Contribution to journalArticle

Prasad, Nikhil K. ; Desy, Nicholas M. ; Howe, B. Matthew ; Amrami, Kimberly K. ; Spinner, Robert J. / Subparaneurial ganglion cysts of the fibular and tibial nerves : A new variant of intraneural ganglion cysts. In: Clinical Anatomy. 2016 ; Vol. 29, No. 4. pp. 530-537.
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