Subacute Sensory Neuronopathy Associated With Small Cell Lung Carcinoma: Diagnosis Aided by Autoimmune Serology

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Abstract

In two patients with subacute sensory neuronopathy associated with small cell carcinoma of the lung, the diagnosis of the paraneoplastic syndrome was aided by the finding, in highly diluted serum (1/500 and 1/2,000, respectively), of unusual and distinctive antinuclear antibodies with reactivity restricted to neuronal nuclei. Magnetic resonance imaging of the chest was instrumental in detecting both lung cancers.

Original languageEnglish (US)
Pages (from-to)29-32
Number of pages4
JournalMayo Clinic proceedings
Volume63
Issue number1
DOIs
StatePublished - Jan 1 1988

ASJC Scopus subject areas

  • Medicine(all)

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