Subacute sensory neuronopathy associated with small cell lung carcinoma: Diagnosis aided by autoimmune serology

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Abstract

In two patients with subacute sensory neuronopathy associated with small cell carcinoma of the lung, the diagnosis of the paraneoplastic syndrome was aided by the finding, in highly diluted serum (1/500 and 1/2,000, respectively), of unusual and distinctive antinuclear antibodies with reacticity restricted to neuronal nuclei. Magnetic resonance imaging of the chest was instrumental in detecting both lung cancers.

Original languageEnglish (US)
Pages (from-to)29-32
Number of pages4
JournalMayo Clinic Proceedings
Volume63
Issue number1
StatePublished - 1988

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Paraneoplastic Syndromes
Antinuclear Antibodies
Small Cell Lung Carcinoma
Serology
Lung Neoplasms
Thorax
Magnetic Resonance Imaging
Serum

ASJC Scopus subject areas

  • Medicine(all)

Cite this

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title = "Subacute sensory neuronopathy associated with small cell lung carcinoma: Diagnosis aided by autoimmune serology",
abstract = "In two patients with subacute sensory neuronopathy associated with small cell carcinoma of the lung, the diagnosis of the paraneoplastic syndrome was aided by the finding, in highly diluted serum (1/500 and 1/2,000, respectively), of unusual and distinctive antinuclear antibodies with reacticity restricted to neuronal nuclei. Magnetic resonance imaging of the chest was instrumental in detecting both lung cancers.",
author = "Kimmel, {D. W.} and O'Neill, {Brian Patrick} and Lennon, {Vanda A}",
year = "1988",
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AU - Kimmel, D. W.

AU - O'Neill, Brian Patrick

AU - Lennon, Vanda A

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N2 - In two patients with subacute sensory neuronopathy associated with small cell carcinoma of the lung, the diagnosis of the paraneoplastic syndrome was aided by the finding, in highly diluted serum (1/500 and 1/2,000, respectively), of unusual and distinctive antinuclear antibodies with reacticity restricted to neuronal nuclei. Magnetic resonance imaging of the chest was instrumental in detecting both lung cancers.

AB - In two patients with subacute sensory neuronopathy associated with small cell carcinoma of the lung, the diagnosis of the paraneoplastic syndrome was aided by the finding, in highly diluted serum (1/500 and 1/2,000, respectively), of unusual and distinctive antinuclear antibodies with reacticity restricted to neuronal nuclei. Magnetic resonance imaging of the chest was instrumental in detecting both lung cancers.

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