TY - JOUR
T1 - Study of critically ill patients with systemic lupus erythematosus
AU - Ansell, Stephen Maxted
AU - Bedhesi, Sunil
AU - Ruff, Brian
AU - Mahomed, Akhter Goolam
AU - Richards, Guy
AU - Mer, Mervyn
AU - Feldman, Charles
PY - 1996/6
Y1 - 1996/6
N2 - Objectives: To determine the presenting features, prognostic factors, course, and outcome of critically ill patients with systemic lupus erythematosus admitted to the intensive care unit (ICU). Design: Retrospective patient record review. Setting: Two academic teaching hospitals. Patients: All patients with systemic lupus erythematosus admitted to the ICUs between January 1982 and July 1993. Measurements and Main Results: There were 28 female and two male patients. Fifteen patients were white, 11 patients were black, and four patients were Asian. The median age was 29 yrs. The reasons for admission to the ICU were multifactorial. However, most patients were admitted for infective, renal, cardiac, or coagulation complications. Despite aggressive management, 16 (53%) patients died in the ICU or shortly after discharge. The median ICU survival rate (admission to death) was 22 days. The only pretreatment factor that predicted a poor outcome was the presence of renal involvement due to systemic lupus erythematosus. Conclusions: Our study suggests that patients with systemic lupus erythematosus admitted to an ICU often have florid disease manifestations with multifactorial reasons precipitating the admission. The prognosis for such patients is poor, particularly in the presence of renal involvement.
AB - Objectives: To determine the presenting features, prognostic factors, course, and outcome of critically ill patients with systemic lupus erythematosus admitted to the intensive care unit (ICU). Design: Retrospective patient record review. Setting: Two academic teaching hospitals. Patients: All patients with systemic lupus erythematosus admitted to the ICUs between January 1982 and July 1993. Measurements and Main Results: There were 28 female and two male patients. Fifteen patients were white, 11 patients were black, and four patients were Asian. The median age was 29 yrs. The reasons for admission to the ICU were multifactorial. However, most patients were admitted for infective, renal, cardiac, or coagulation complications. Despite aggressive management, 16 (53%) patients died in the ICU or shortly after discharge. The median ICU survival rate (admission to death) was 22 days. The only pretreatment factor that predicted a poor outcome was the presence of renal involvement due to systemic lupus erythematosus. Conclusions: Our study suggests that patients with systemic lupus erythematosus admitted to an ICU often have florid disease manifestations with multifactorial reasons precipitating the admission. The prognosis for such patients is poor, particularly in the presence of renal involvement.
KW - critical illness
KW - intensive care units
KW - lupus erythematosus
KW - outcome
KW - patient outcome assessment
KW - prognosis
KW - renal disease
KW - systemic
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U2 - 10.1097/00003246-199606000-00018
DO - 10.1097/00003246-199606000-00018
M3 - Article
C2 - 8681602
AN - SCOPUS:0029895417
SN - 0090-3493
VL - 24
SP - 981
EP - 984
JO - Critical care medicine
JF - Critical care medicine
IS - 6
ER -