Study of critically ill patients with systemic lupus erythematosus

Stephen Maxted Ansell, Sunil Bedhesi, Brian Ruff, Akhter Goolam Mahomed, Guy Richards, Mervyn Mer, Charles Feldman

Research output: Contribution to journalArticle

37 Scopus citations

Abstract

Objectives: To determine the presenting features, prognostic factors, course, and outcome of critically ill patients with systemic lupus erythematosus admitted to the intensive care unit (ICU). Design: Retrospective patient record review. Setting: Two academic teaching hospitals. Patients: All patients with systemic lupus erythematosus admitted to the ICUs between January 1982 and July 1993. Measurements and Main Results: There were 28 female and two male patients. Fifteen patients were white, 11 patients were black, and four patients were Asian. The median age was 29 yrs. The reasons for admission to the ICU were multifactorial. However, most patients were admitted for infective, renal, cardiac, or coagulation complications. Despite aggressive management, 16 (53%) patients died in the ICU or shortly after discharge. The median ICU survival rate (admission to death) was 22 days. The only pretreatment factor that predicted a poor outcome was the presence of renal involvement due to systemic lupus erythematosus. Conclusions: Our study suggests that patients with systemic lupus erythematosus admitted to an ICU often have florid disease manifestations with multifactorial reasons precipitating the admission. The prognosis for such patients is poor, particularly in the presence of renal involvement.

Original languageEnglish (US)
Pages (from-to)981-984
Number of pages4
JournalCritical care medicine
Volume24
Issue number6
DOIs
StatePublished - Jun 1 1996

Keywords

  • critical illness
  • intensive care units
  • lupus erythematosus
  • outcome
  • patient outcome assessment
  • prognosis
  • renal disease
  • systemic

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

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    Ansell, S. M., Bedhesi, S., Ruff, B., Mahomed, A. G., Richards, G., Mer, M., & Feldman, C. (1996). Study of critically ill patients with systemic lupus erythematosus. Critical care medicine, 24(6), 981-984. https://doi.org/10.1097/00003246-199606000-00018