Glutaraldehyde fixation after death of the animal (simulated autopsy) was associated with a statistically significant change of the relationship between transverse area of axis cylinder and number of myelin lamellae from that in the controls (simulated biopsy). Differences in length of time elapsed prior to glutaraldehyde fixation (1, 6, or 12 hr) had no significant effect. When the fixation was begun after death, in fibers with more than 72 myelin lamellae the area of axis cylinder was smaller, but in fibers with less than 71 myelin lamellae it was larger than in controls.
ASJC Scopus subject areas
- Clinical Neurology