Studies to improve fixation of human nerves. Part 2. Effect of time elapsed between death and glutaraldehyde fixation on relationship of axonal area to number of myelin lamellae

Akio Ohnishi, Peter C. O'Brien, Peter James Dyck

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

Glutaraldehyde fixation after death of the animal (simulated autopsy) was associated with a statistically significant change of the relationship between transverse area of axis cylinder and number of myelin lamellae from that in the controls (simulated biopsy). Differences in length of time elapsed prior to glutaraldehyde fixation (1, 6, or 12 hr) had no significant effect. When the fixation was begun after death, in fibers with more than 72 myelin lamellae the area of axis cylinder was smaller, but in fibers with less than 71 myelin lamellae it was larger than in controls.

Original languageEnglish (US)
Pages (from-to)387-390
Number of pages4
JournalJournal of the neurological sciences
Volume23
Issue number3
DOIs
StatePublished - Nov 1974

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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