Moschus moschiferus (musk) had significant antiinflammatory activity in carrageenin induced edema, formaline arthritis and adjuvant arthritis. It was more potent than hydrocortisone and phenyl butazone in adjuvant arthritis. The secondary lesions produced in adjuvant arthritis were mild in musk and phenylbutazone treated groups in comparison to the moderate lesions in hydrocortisone treated group. Also, the weight loss was less in musk and phenylbutazone treated groups. Musk failed to prolong the survival time of the adrenalectomized rats. It significantly decreased the histamine and the 5 HT content of the inflamed paw of the rats. No hematological changes were observed.
|Original language||English (US)|
|Number of pages||7|
|Journal||Indian Journal of Physiology and Pharmacology|
|State||Published - Dec 1 1973|
ASJC Scopus subject areas
- Physiology (medical)