Stroke detection with 3 different PET tracers

Ayca Dundar, Michael S. Bold, Busranur Agac, Ayse Tuba Kendi, Saul N. Friedman

Research output: Contribution to journalArticle

Abstract

Stroke is a common cause of patient morbidity and mortality, being the fifth leading cause of death in the United States. Positron emission tomography (PET) is a proven tool for oncology patients, and may have utility in patients with stroke. We demonstrate findings of stroke incidentally detected on oncologic PET/CTs using 18F-FDG, 11C-Choline, and 68Ga-DOTATATE radiotracers. Specifically, focal 11C-Choline or 68Ga-DOTATATE uptakes localized in areas of MRI confirmed ischemia, and paradoxically increased 18F-FDG activity was visualized surrounding a region of hemorrhage, in different patients. These cases demonstrate that PET may have utility in evaluating patients with stroke based on flow dynamics, metabolic activity, and receptor expression.

Original languageEnglish (US)
Pages (from-to)1447-1451
Number of pages5
JournalRadiology Case Reports
Volume14
Issue number11
DOIs
StatePublished - Nov 2019

Keywords

  • 11C-Choline
  • 18F-FDG
  • 68Ga-DOTATATE
  • PET
  • Stroke

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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    Dundar, A., Bold, M. S., Agac, B., Kendi, A. T., & Friedman, S. N. (2019). Stroke detection with 3 different PET tracers. Radiology Case Reports, 14(11), 1447-1451. https://doi.org/10.1016/j.radcr.2019.09.005