TY - JOUR
T1 - Stressing the Cardiopulmonary Vascular System
T2 - The Role of Echocardiography
AU - Rudski, Lawrence G.
AU - Gargani, Luna
AU - Armstrong, William F.
AU - Lancellotti, Patrizio
AU - Lester, Steven J.
AU - Grünig, Ekkehard
AU - D'Alto, Michele
AU - Åström Aneq, Meriam
AU - Ferrara, Francesco
AU - Saggar, Rajeev
AU - Saggar, Rajan
AU - Naeije, Robert
AU - Picano, Eugenio
AU - Schiller, Nelson B.
AU - Bossone, Eduardo
N1 - Publisher Copyright:
© 2018 American Society of Echocardiography
PY - 2018/5
Y1 - 2018/5
N2 - The cardiopulmonary vascular system represents a key determinant of prognosis in several cardiorespiratory diseases. Although right heart catheterization is considered the gold standard for assessing pulmonary hemodynamics, a comprehensive noninvasive evaluation including left and right ventricular reserve and function and cardiopulmonary interactions remains highly attractive. Stress echocardiography is crucial in the evaluation of many cardiac conditions, typically coronary artery disease but also heart failure and valvular heart disease. In stress echocardiographic applications beyond coronary artery disease, the assessment of the cardiopulmonary vascular system is a cornerstone. The possibility of coupling the left and right ventricles with the pulmonary circuit during stress can provide significant insight into cardiopulmonary physiology in healthy and diseased subjects, can support the diagnosis of the etiology of pulmonary hypertension and other conditions, and can offer valuable prognostic information. In this state-of-the-art document, the topic of stress echocardiography applied to the cardiopulmonary vascular system is thoroughly addressed, from pathophysiology to different stress modalities and echocardiographic parameters, from clinical applications to limitations and future directions.
AB - The cardiopulmonary vascular system represents a key determinant of prognosis in several cardiorespiratory diseases. Although right heart catheterization is considered the gold standard for assessing pulmonary hemodynamics, a comprehensive noninvasive evaluation including left and right ventricular reserve and function and cardiopulmonary interactions remains highly attractive. Stress echocardiography is crucial in the evaluation of many cardiac conditions, typically coronary artery disease but also heart failure and valvular heart disease. In stress echocardiographic applications beyond coronary artery disease, the assessment of the cardiopulmonary vascular system is a cornerstone. The possibility of coupling the left and right ventricles with the pulmonary circuit during stress can provide significant insight into cardiopulmonary physiology in healthy and diseased subjects, can support the diagnosis of the etiology of pulmonary hypertension and other conditions, and can offer valuable prognostic information. In this state-of-the-art document, the topic of stress echocardiography applied to the cardiopulmonary vascular system is thoroughly addressed, from pathophysiology to different stress modalities and echocardiographic parameters, from clinical applications to limitations and future directions.
KW - Cardiopulmonary vascular system
KW - Pulmonary circulation
KW - Pulmonary hypertension
KW - Right heart
KW - Stress echocardiography
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U2 - 10.1016/j.echo.2018.01.002
DO - 10.1016/j.echo.2018.01.002
M3 - Review article
C2 - 29573927
AN - SCOPUS:85044277667
VL - 31
SP - 527-550.e11
JO - Journal of the American Society of Echocardiography
JF - Journal of the American Society of Echocardiography
SN - 0894-7317
IS - 5
ER -