Strategy for prevention of cancers of the esophagus

Junichi Akiyama, Leo Alexandre, Anushka Baruah, Navtej Buttar, Raghav Chandra, Allan B. Clark, Andrew R. Hart, Ernest Hawk, Daniela Kandioler, Sonja Kappel, Sheila K. Krishnadath, Anamay Sharma, Ishtpreet Singh, Danielle Straub, George Triadafilopoulos, Asad Umar, Brigitte Wolf

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

The following, from the 12th OESO World Conference: Cancers of the Esophagus, includes commentaries on the animal reflux-inflammation models for Barrett's esophagus and esophageal adenocarcinoma; genomic/epigenomic analyses; eflornithine-based combinations; the molecular derangements that promote neoplastic transformation; the role of COX-2 inhibitors, proton pump inhibitors, and phase II trials in Barrett's adenocarcinoma; statins in chemoprevention and treatment of esophageal cancer; and biomarkers as potential targets in Barrett's adenocarcinoma.

Original languageEnglish (US)
Pages (from-to)108-126
Number of pages19
JournalAnnals of the New York Academy of Sciences
Volume1325
Issue number1
DOIs
StatePublished - Sep 1 2014

Keywords

  • Animal reflux-inflammation models
  • Barrett's adenocarcinoma
  • Biomarkers
  • COXIBs, PPIs
  • Elofrnithine
  • OESO
  • Statins

ASJC Scopus subject areas

  • Neuroscience(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • History and Philosophy of Science

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  • Cite this

    Akiyama, J., Alexandre, L., Baruah, A., Buttar, N., Chandra, R., Clark, A. B., Hart, A. R., Hawk, E., Kandioler, D., Kappel, S., Krishnadath, S. K., Sharma, A., Singh, I., Straub, D., Triadafilopoulos, G., Umar, A., & Wolf, B. (2014). Strategy for prevention of cancers of the esophagus. Annals of the New York Academy of Sciences, 1325(1), 108-126. https://doi.org/10.1111/nyas.12529