Strategies for targeting therapeutic gene delivery

Research output: Contribution to journalReview article

30 Scopus citations

Abstract

A major goal for gene therapy is to obtain targeted vectors that transfer genes efficiently to specific cell types. In theory, this can be achieved by targeting entry of the vector or by building gene expression cassettes that restrict gene expression to certain cell types. This review summarizes recent strategies to alter vector tropism for targeted gene delivery.

Original languageEnglish (US)
Pages (from-to)448-453
Number of pages6
JournalMolecular Medicine Today
Volume5
Issue number10
DOIs
StatePublished - Oct 1 1999

ASJC Scopus subject areas

  • Molecular Medicine
  • Genetics

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