Stimulation of tyrosine hydroxylase activity in an adrenergic clone of mouse neuroblastoma by dibutyryl cyclic AMP

E. Richelson

Research output: Chapter in Book/Report/Conference proceedingChapter

75 Scopus citations

Abstract

The results show that dibutyryl cyclic AMP stimulates tyrosine hydroxylase activity in an adrenergic clone of mouse neuroblastoma. This effect of dibutyryl cyclic AMP seems in part to be independent of its ability to slow cell division. Sodium butyrate, however, seems to increase tyrosine hydroxylase activity by inhibiting cell division. Prostaglandin PGE1 which has been reported to increase intracellular levels of cyclic AMP in clones of mouse neuroblastoma did not affect tyrosine hydroxylase activity to the same extent as dibutyryl cyclic AMP.

Original languageEnglish (US)
Title of host publicationNATURE NEW BIOL.
Pages175-177
Number of pages3
Volume242
Edition119
StatePublished - 1973
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Stimulation of tyrosine hydroxylase activity in an adrenergic clone of mouse neuroblastoma by dibutyryl cyclic AMP'. Together they form a unique fingerprint.

  • Cite this

    Richelson, E. (1973). Stimulation of tyrosine hydroxylase activity in an adrenergic clone of mouse neuroblastoma by dibutyryl cyclic AMP. In NATURE NEW BIOL. (119 ed., Vol. 242, pp. 175-177)