TY - JOUR
T1 - Stimulating Solutions for Intractable Epilepsy
AU - Denison, Timothy
AU - Koubeissi, Mohamad
AU - Krook-Magnuson, Esther
AU - Mogul, David
AU - Worrell, Gregory
AU - Schevon, Catherine
N1 - Publisher Copyright:
© The Author(s) 2021.
PY - 2021/10
Y1 - 2021/10
N2 - Implantable devices for controlling medically intractable seizures nondestructively are rapidly advancing. These offer reversible, potentially, restorative options beyond traditional, surgical procedures, which rely, largely on resection or ablation of selected brain sites. Several lines of, investigation aimed at improving efficacy of these devices are discussed, ranging from identifying novel subcortical, white matter, or cell-type specific targets to engineering advances for adaptive techniques based- on continuous, dynamic system analysis.
AB - Implantable devices for controlling medically intractable seizures nondestructively are rapidly advancing. These offer reversible, potentially, restorative options beyond traditional, surgical procedures, which rely, largely on resection or ablation of selected brain sites. Several lines of, investigation aimed at improving efficacy of these devices are discussed, ranging from identifying novel subcortical, white matter, or cell-type specific targets to engineering advances for adaptive techniques based- on continuous, dynamic system analysis.
KW - electrical stimulation
KW - epileptic networks
KW - intractable epilepsy
KW - next-generation devices
KW - therapeutic devices
UR - http://www.scopus.com/inward/record.url?scp=85105759476&partnerID=8YFLogxK
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U2 - 10.1177/15357597211012466
DO - 10.1177/15357597211012466
M3 - Article
AN - SCOPUS:85105759476
SN - 1535-7597
VL - 21
SP - 315
EP - 319
JO - Epilepsy Currents
JF - Epilepsy Currents
IS - 5
ER -