Stereotactic radiosurgery for arteriovenous malformations: The effect of treatment period on patient outcomes

Bruce E. Pollock, Michael J. Link, Scott L. Stafford, Yolanda Isabel Garces, Robert L. Foote

Research output: Contribution to journalArticle

17 Scopus citations

Abstract

BACKGROUND: Stereotactic radiosurgery (SRS) has been performed on patients with cerebral arteriovenous malformations (AVMs) for over 40 years. OBJECTIVE: To evaluate the impact of treatment period on obliteration, intracranial hemorrhage (ICH), and radiation-induced complications (RICs). METHODS: Retrospective comparison of 381 AVM patients having SRS during a 20-year period (group 1, January 1990 through March 1997, n 160; group 2, April 1997 through December 2009, n 221). The median radiological and clinical follow-up after initial SRS was 77 months and 93 months, respectively. RESULTS: Obliteration was 59.1% at 4 years and 85.1% at 8 years. Obliteration was more common in patients with hemispheric or cerebellar AVMs (P .001), smaller prescription isodose volume (PIV) (P

Original languageEnglish (US)
Pages (from-to)499-508
Number of pages10
JournalNeurosurgery
Volume78
Issue number4
DOIs
StatePublished - Apr 1 2016

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Keywords

  • Arteriovenous malformation
  • Complications
  • Hemorrhage
  • Obliteration rate
  • Stereotactic radiosurgery

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

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