Stent placement for the treatment of occlusive atherosclerotic carotid artery disease in patients with concomitant coronary artery disease

Demetrius K. Lopes, Robert A. Mericle, Giuseppe Lanzino, Ajay K. Wakhloo, Lee R. Guterman, L. Nelson Hopkins

Research output: Contribution to journalArticle

56 Citations (Scopus)

Abstract

Object. The authors report their experience with carotid artery stent placement (CASP) in patients with concomitant carotid artery (CA) and coronary artery (CorA) diseases. Methods. In a review of 320 consecutive patients who underwent CASP, the authors identified 49 with severe CorA disease in addition to significant CA stenosis, who had undergone CASP before planned CorA bypass grafting (CorABG). The average age of these 49 patients was 68 years. In 39 patients (80%) the New York Heart Association functional classification grade was IV and in 10 the grade was III. In 26 patients 50% or greater stenosis of the left main CorA was found. Seventeen patients (35%) suffered from either significant hemodynamic contralateral CA stenosis (> 60% stenosis; eight patients) or contralateral CA occlusion (nine patients). Sixteen patients (33%) had symptomatic CA disease. No cerebrovascular events occurred during CorABG. Four patients (8%) died of cardiac arrest and one patient (2%) suffered a major stroke within 30 days after the CorABG procedure. No patient experienced clinically significant recurrent CA stenosis during the study period (average clinical follow-up period 27 months). Conclusions. Carotid artery stent placement should be considered as an alternative for the management of concomitant CA and CorA diseases. These preliminary results support the feasibility and durability of CASP in the population studied.

Original languageEnglish (US)
Pages (from-to)490-496
Number of pages7
JournalJournal of Neurosurgery
Volume96
Issue number3
StatePublished - 2002
Externally publishedYes

Fingerprint

Carotid Artery Diseases
Stents
Coronary Artery Disease
Carotid Arteries
Carotid Stenosis
Therapeutics
Pathologic Constriction
Heart Arrest
Coronary Artery Bypass
Coronary Vessels
Hemodynamics
Stroke

Keywords

  • Carotid artery disease
  • Coronary artery bypass grafting
  • Coronary artery disease
  • Endovascular therapy
  • Stent
  • Stroke

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Lopes, D. K., Mericle, R. A., Lanzino, G., Wakhloo, A. K., Guterman, L. R., & Hopkins, L. N. (2002). Stent placement for the treatment of occlusive atherosclerotic carotid artery disease in patients with concomitant coronary artery disease. Journal of Neurosurgery, 96(3), 490-496.

Stent placement for the treatment of occlusive atherosclerotic carotid artery disease in patients with concomitant coronary artery disease. / Lopes, Demetrius K.; Mericle, Robert A.; Lanzino, Giuseppe; Wakhloo, Ajay K.; Guterman, Lee R.; Hopkins, L. Nelson.

In: Journal of Neurosurgery, Vol. 96, No. 3, 2002, p. 490-496.

Research output: Contribution to journalArticle

Lopes, DK, Mericle, RA, Lanzino, G, Wakhloo, AK, Guterman, LR & Hopkins, LN 2002, 'Stent placement for the treatment of occlusive atherosclerotic carotid artery disease in patients with concomitant coronary artery disease', Journal of Neurosurgery, vol. 96, no. 3, pp. 490-496.
Lopes, Demetrius K. ; Mericle, Robert A. ; Lanzino, Giuseppe ; Wakhloo, Ajay K. ; Guterman, Lee R. ; Hopkins, L. Nelson. / Stent placement for the treatment of occlusive atherosclerotic carotid artery disease in patients with concomitant coronary artery disease. In: Journal of Neurosurgery. 2002 ; Vol. 96, No. 3. pp. 490-496.
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