Stenotrophomonas maltophilia meningitis: Report of two cases and review of the literature

Konstantinos Papadakis, Shahe E. Vartivarian, Maria Vassilaki, Elias J. Anaissie

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

The authors report two cases of meningitis caused by Stenotrophomonas maltophilia in cancer patients following placement of an Ommaya reservoir for treatment of meningeal carcinomatosis. In addition, they review eight other cases of S. maltophilia that have been reported to date. Stenotrophomonas maltophilia meningitis is often associated with neurosurgical procedures: however, spontaneous infection may also occur, mainly in neonates. The disease's clinical presentation is similar to that of other forms of meningitis caused by Gram-negative bacilli. The overall mortality rate of this disease is 20% and is limited to neonates with spontaneous meningitis in whom effective antibiotic therapy is delayed. Meningitis caused by S. maltophilia in the modern era should be considered in immunocompromised hosts with significant central nervous system disease who have undergone neurosurgical procedures and who do not readily respond to broad-spectrum antimicrobial coverage.

Original languageEnglish (US)
Pages (from-to)106-108
Number of pages3
JournalJournal of Neurosurgery
Volume87
Issue number1
DOIs
StatePublished - Jan 1 1997
Externally publishedYes

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Stenotrophomonas maltophilia
Meningitis
Neurosurgical Procedures
Meningeal Carcinomatosis
Newborn Infant
Central Nervous System Diseases
Immunocompromised Host
Bacillus
Anti-Bacterial Agents
Mortality
Therapeutics
Infection
Neoplasms

Keywords

  • Meningitis
  • Postoperative infection
  • Stenotrophomonas maltophilia

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Cite this

Stenotrophomonas maltophilia meningitis : Report of two cases and review of the literature. / Papadakis, Konstantinos; Vartivarian, Shahe E.; Vassilaki, Maria; Anaissie, Elias J.

In: Journal of Neurosurgery, Vol. 87, No. 1, 01.01.1997, p. 106-108.

Research output: Contribution to journalArticle

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