Stem Cell-Related Studies and Stem Cell-Based Therapies in Liver Diseases

Wei Zhou, Erek D. Nelson, Anan A. Abu Rmilah, Bruce P. Amiot, Scott L. Nyberg

Research output: Contribution to journalReview article

Abstract

Owing to the increasing worldwide burden of liver diseases, the crucial need for safe and effective interventions for treating end-stage liver failure has been a very productive line of inquiry in the discipline of hepatology for many years. Liver transplantation is recognized as the most effective treatment for end-stage liver disease; however, the shortage of donor organs, high medical costs, and lifelong use of immunosuppressive agents represent major drawbacks and demand exploration for alternative treatments. Stem cell-based therapies have been widely studied in the field of liver diseases and are considered to be among the most promising therapies. Herein, we review recent advances in the application of stem cell-related therapies in liver disease with the aim of providing readers with relevant knowledge in this field and inspiration to spur further inquiry.

Original languageEnglish (US)
Pages (from-to)1116-1122
Number of pages7
JournalCell transplantation
Volume28
Issue number9-10
DOIs
StatePublished - Sep 1 2019

Keywords

  • cellular therapy
  • hepatology

ASJC Scopus subject areas

  • Biomedical Engineering
  • Cell Biology
  • Transplantation

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