Stem Cell Mobilization and Autologous Transplant for Immunoglobulin Light-Chain Amyloidosis

Morie A. Gertz, Stefan Schonland

Research output: Contribution to journalReview articlepeer-review

Abstract

Stem cell transplantation was one of the first proven effective regimens for the management of immunoglobulin light-chain amyloidosis. Criteria for patient selection and the mobilization regimen become important features in ensuring a safe outcome. The technique of stem cell transplantation has evolved considerably in parallel with the development of new chemotherapeutic agents for the management of amyloidosis. Optimal outcomes require both the use of effective novel agent induction and appropriate application of high-dose chemotherapy with subsequent stem cell reconstitution.

Original languageEnglish (US)
Pages (from-to)1133-1144
Number of pages12
JournalHematology/Oncology Clinics of North America
Volume34
Issue number6
DOIs
StateAccepted/In press - 2020

Keywords

  • High-dose chemotherapy
  • Melphalan
  • Mobilization
  • Transplantation

ASJC Scopus subject areas

  • Hematology
  • Oncology

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