Stem cell lineage specification: You become what you eat

Research output: Contribution to journalShort survey

3 Scopus citations

Abstract

Nutrient availability and intermediate metabolism are increasingly recognized to govern stem cell behavior. Oburoglu et al. (2014) now demonstrate that glutamine- and glucose-dependent nucleotide synthesis segregate erythroid versus myeloid differentiation during hematopoietic stem cell specification, implicating a metabolism-centric regulation of lineage choices.

Original languageEnglish (US)
Pages (from-to)389-391
Number of pages3
JournalCell Metabolism
Volume20
Issue number3
DOIs
StatePublished - Sep 2 2014

ASJC Scopus subject areas

  • Physiology
  • Molecular Biology
  • Cell Biology

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