Stem cell lineage specification: You become what you eat

Clifford D.L. Folmes; Andre Terzic

doi:10.1016/j.cmet.2014.08.006

Stem cell lineage specification: You become what you eat

Clifford D.L. Folmes, Andre Terzic

Research output: Contribution to journal › Short survey › peer-review

4 Scopus citations

Abstract

Nutrient availability and intermediate metabolism are increasingly recognized to govern stem cell behavior. Oburoglu et al. (2014) now demonstrate that glutamine- and glucose-dependent nucleotide synthesis segregate erythroid versus myeloid differentiation during hematopoietic stem cell specification, implicating a metabolism-centric regulation of lineage choices.

Original language	English (US)
Pages (from-to)	389-391
Number of pages	3
Journal	Cell Metabolism
Volume	20
Issue number	3
DOIs	https://doi.org/10.1016/j.cmet.2014.08.006
State	Published - Sep 2 2014

ASJC Scopus subject areas

Physiology
Molecular Biology
Cell Biology

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title = "Stem cell lineage specification: You become what you eat",

abstract = "Nutrient availability and intermediate metabolism are increasingly recognized to govern stem cell behavior. Oburoglu et al. (2014) now demonstrate that glutamine- and glucose-dependent nucleotide synthesis segregate erythroid versus myeloid differentiation during hematopoietic stem cell specification, implicating a metabolism-centric regulation of lineage choices.",

author = "Folmes, {Clifford D.L.} and Andre Terzic",

year = "2014",

month = sep,

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doi = "10.1016/j.cmet.2014.08.006",

language = "English (US)",

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pages = "389--391",

journal = "Cell Metabolism",

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T2 - You become what you eat

AU - Folmes, Clifford D.L.

AU - Terzic, Andre

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N2 - Nutrient availability and intermediate metabolism are increasingly recognized to govern stem cell behavior. Oburoglu et al. (2014) now demonstrate that glutamine- and glucose-dependent nucleotide synthesis segregate erythroid versus myeloid differentiation during hematopoietic stem cell specification, implicating a metabolism-centric regulation of lineage choices.

AB - Nutrient availability and intermediate metabolism are increasingly recognized to govern stem cell behavior. Oburoglu et al. (2014) now demonstrate that glutamine- and glucose-dependent nucleotide synthesis segregate erythroid versus myeloid differentiation during hematopoietic stem cell specification, implicating a metabolism-centric regulation of lineage choices.

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DO - 10.1016/j.cmet.2014.08.006

M3 - Short survey

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SN - 1550-4131

VL - 20

SP - 389

EP - 391

JO - Cell Metabolism

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ER -

Stem cell lineage specification: You become what you eat

Abstract

ASJC Scopus subject areas

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