Statement for gastroesophageal reflux disease after peroral endoscopic myotomy from an international multicenter experience

Haruhiro Inoue, Hironari Shiwaku, Yasutoshi Kobayashi, Philip W.Y. Chiu, Robert H. Hawes, Horst Neuhaus, Guido Costamagna, Stavros N. Stavropoulos, Norio Fukami, Stefan Seewald, Manabu Onimaru, Hitomi Minami, Shinwa Tanaka, Yuto Shimamura, Esperanza Grace Santi, Kevin Grimes, Hisao Tajiri

Research output: Contribution to journalReview article

Abstract

It has been 10 years since peroral endoscopic myotomy (POEM) was reported for the first time, and POEM has currently become the standard treatment for achalasia and related disorders globally because it is less invasive and has a higher curative effect than conventional therapeutic methods. However, there are limited studies comparing the long-term outcomes of POEM with those of conventional therapeutic methods, particularly in the occurrence of gastroesophageal reflux disease (GERD) after therapy. With this background, we held a consensus meeting to discuss the pathophysiology and management of GERD after POEM based on published papers and experiences of each expert and to discuss the prevention of GERD and dealing with anti-acid drug refractory GERD. This meeting was held on April 27, 2018 in Tokyo to establish statements and finalize the recommendations using the modified Delphi method. This manuscript presents eight statements regarding GERD after POEM.

Original languageEnglish (US)
JournalEsophagus
DOIs
StateAccepted/In press - Jan 1 2019

Fingerprint

Gastroesophageal Reflux
Esophageal Achalasia
Tokyo
Therapeutic Uses
Acids
Therapeutics
Pharmaceutical Preparations

Keywords

  • Achalasia
  • GERD
  • Myotomy

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Inoue, H., Shiwaku, H., Kobayashi, Y., Chiu, P. W. Y., Hawes, R. H., Neuhaus, H., ... Tajiri, H. (Accepted/In press). Statement for gastroesophageal reflux disease after peroral endoscopic myotomy from an international multicenter experience. Esophagus. https://doi.org/10.1007/s10388-019-00689-6

Statement for gastroesophageal reflux disease after peroral endoscopic myotomy from an international multicenter experience. / Inoue, Haruhiro; Shiwaku, Hironari; Kobayashi, Yasutoshi; Chiu, Philip W.Y.; Hawes, Robert H.; Neuhaus, Horst; Costamagna, Guido; Stavropoulos, Stavros N.; Fukami, Norio; Seewald, Stefan; Onimaru, Manabu; Minami, Hitomi; Tanaka, Shinwa; Shimamura, Yuto; Santi, Esperanza Grace; Grimes, Kevin; Tajiri, Hisao.

In: Esophagus, 01.01.2019.

Research output: Contribution to journalReview article

Inoue, H, Shiwaku, H, Kobayashi, Y, Chiu, PWY, Hawes, RH, Neuhaus, H, Costamagna, G, Stavropoulos, SN, Fukami, N, Seewald, S, Onimaru, M, Minami, H, Tanaka, S, Shimamura, Y, Santi, EG, Grimes, K & Tajiri, H 2019, 'Statement for gastroesophageal reflux disease after peroral endoscopic myotomy from an international multicenter experience', Esophagus. https://doi.org/10.1007/s10388-019-00689-6
Inoue, Haruhiro ; Shiwaku, Hironari ; Kobayashi, Yasutoshi ; Chiu, Philip W.Y. ; Hawes, Robert H. ; Neuhaus, Horst ; Costamagna, Guido ; Stavropoulos, Stavros N. ; Fukami, Norio ; Seewald, Stefan ; Onimaru, Manabu ; Minami, Hitomi ; Tanaka, Shinwa ; Shimamura, Yuto ; Santi, Esperanza Grace ; Grimes, Kevin ; Tajiri, Hisao. / Statement for gastroesophageal reflux disease after peroral endoscopic myotomy from an international multicenter experience. In: Esophagus. 2019.
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AB - It has been 10 years since peroral endoscopic myotomy (POEM) was reported for the first time, and POEM has currently become the standard treatment for achalasia and related disorders globally because it is less invasive and has a higher curative effect than conventional therapeutic methods. However, there are limited studies comparing the long-term outcomes of POEM with those of conventional therapeutic methods, particularly in the occurrence of gastroesophageal reflux disease (GERD) after therapy. With this background, we held a consensus meeting to discuss the pathophysiology and management of GERD after POEM based on published papers and experiences of each expert and to discuss the prevention of GERD and dealing with anti-acid drug refractory GERD. This meeting was held on April 27, 2018 in Tokyo to establish statements and finalize the recommendations using the modified Delphi method. This manuscript presents eight statements regarding GERD after POEM.

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