Standardized drug and pharmacological class network construction

Qian Zhu, Guoqian D Jiang, Liwei Wang, Christopher G. Chute

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Citations (Scopus)

Abstract

Dozens of drug terminologies and resources capture the drug and/or drug class information, ranging from their coverage and adequacy of representation. No transformative ways are available to link them together in a standard way, which hinders data integration and data representation for drug-related clinical and translational studies. In this paper, we introduce our preliminary work for building a standardized drug and drug class network that integrates multiple drug terminological resources, using Anatomical Therapeutic Chemical (ATC) and National Drug File Reference Terminology (NDF-RT) as network backbone, and expanding with RxNorm and Structured Product Label (SPL). The network consists of 39,728 drugs and drug classes. We calculated and compared structure similarity for each drug/drug class pair from ATC and NDF-RT, and analyzed constructed drug class network from chemical structure perspective.

Original languageEnglish (US)
Title of host publicationStudies in Health Technology and Informatics
Pages1125
Number of pages1
Volume192
Edition1-2
DOIs
StatePublished - 2013
Event14th World Congress on Medical and Health Informatics, MEDINFO 2013 - Copenhagen, Denmark
Duration: Aug 20 2013Aug 23 2013

Other

Other14th World Congress on Medical and Health Informatics, MEDINFO 2013
CountryDenmark
CityCopenhagen
Period8/20/138/23/13

Fingerprint

Terminology
Pharmacology
Pharmaceutical Preparations
Data integration
Labels
RxNorm

ASJC Scopus subject areas

  • Biomedical Engineering
  • Health Informatics
  • Health Information Management

Cite this

Zhu, Q., Jiang, G. D., Wang, L., & Chute, C. G. (2013). Standardized drug and pharmacological class network construction. In Studies in Health Technology and Informatics (1-2 ed., Vol. 192, pp. 1125) https://doi.org/10.3233/978-1-61499-289-9-1125

Standardized drug and pharmacological class network construction. / Zhu, Qian; Jiang, Guoqian D; Wang, Liwei; Chute, Christopher G.

Studies in Health Technology and Informatics. Vol. 192 1-2. ed. 2013. p. 1125.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Zhu, Q, Jiang, GD, Wang, L & Chute, CG 2013, Standardized drug and pharmacological class network construction. in Studies in Health Technology and Informatics. 1-2 edn, vol. 192, pp. 1125, 14th World Congress on Medical and Health Informatics, MEDINFO 2013, Copenhagen, Denmark, 8/20/13. https://doi.org/10.3233/978-1-61499-289-9-1125
Zhu Q, Jiang GD, Wang L, Chute CG. Standardized drug and pharmacological class network construction. In Studies in Health Technology and Informatics. 1-2 ed. Vol. 192. 2013. p. 1125 https://doi.org/10.3233/978-1-61499-289-9-1125
Zhu, Qian ; Jiang, Guoqian D ; Wang, Liwei ; Chute, Christopher G. / Standardized drug and pharmacological class network construction. Studies in Health Technology and Informatics. Vol. 192 1-2. ed. 2013. pp. 1125
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