Stabilization of protein structures

Byungkook Lee; George Vasmatzis

doi:10.1016/S0958-1669(97)80063-8

Stabilization of protein structures

Byungkook Lee, George Vasmatzis

Research output: Contribution to journal › Article › peer-review

55 Scopus citations

Abstract

The technique of protein stabilization has been improving steadily in recent years, but it is only in the past year or two that the stability of some protein molecules has been improved to the level of those from extreme thermophilic organisms. This was achieved by multiple mutations and often by utilizing the knowledge gained from the homologous protein structures from extreme thermophiles.

Original language	English (US)
Pages (from-to)	423-428
Number of pages	6
Journal	Current Opinion in Biotechnology
Volume	8
Issue number	4
DOIs	https://doi.org/10.1016/S0958-1669(97)80063-8
State	Published - Aug 1997

ASJC Scopus subject areas

Biotechnology
Bioengineering
Biomedical Engineering

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10.1016/S0958-1669(97)80063-8

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title = "Stabilization of protein structures",

abstract = "The technique of protein stabilization has been improving steadily in recent years, but it is only in the past year or two that the stability of some protein molecules has been improved to the level of those from extreme thermophilic organisms. This was achieved by multiple mutations and often by utilizing the knowledge gained from the homologous protein structures from extreme thermophiles.",

author = "Byungkook Lee and George Vasmatzis",

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AB - The technique of protein stabilization has been improving steadily in recent years, but it is only in the past year or two that the stability of some protein molecules has been improved to the level of those from extreme thermophilic organisms. This was achieved by multiple mutations and often by utilizing the knowledge gained from the homologous protein structures from extreme thermophiles.

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Stabilization of protein structures

Abstract

ASJC Scopus subject areas

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