Stabilization of protein structures

Byungkook Lee, George Vasmatzis

Research output: Contribution to journalArticle

54 Scopus citations

Abstract

The technique of protein stabilization has been improving steadily in recent years, but it is only in the past year or two that the stability of some protein molecules has been improved to the level of those from extreme thermophilic organisms. This was achieved by multiple mutations and often by utilizing the knowledge gained from the homologous protein structures from extreme thermophiles.

Original languageEnglish (US)
Pages (from-to)423-428
Number of pages6
JournalCurrent Opinion in Biotechnology
Volume8
Issue number4
DOIs
StatePublished - Aug 1997

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Biomedical Engineering

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