Malignant neoplasia frequently occurs with Fanconi anemia. Generally this represents hematologic disease; however, solid tumors may also appear. The woman described here developed squamous cell carcinoma of the vulva at age 28, and is the third such case in a patient with Fanconi anemia that has been reported. It is a diagnosis to be considered for the young patient with this type of carcinoma. Increased chromosomal breakage in this syndrome may be important in the pathogenesis of these neoplastic changes.
|Original language||English (US)|
|Number of pages||3|
|Journal||International Journal of Gynecology and Obstetrics|
|State||Published - Jan 1 1980|
ASJC Scopus subject areas
- Obstetrics and Gynecology