Squamous cell carcinoma of the buccal mucosa: Analysis of prognostic factors

Marshall M. Urist, Christopher J. O'Brien, Seng Jaw Soong, Daniel W Visscher, William A. Maddox

Research output: Contribution to journalArticle

101 Citations (Scopus)

Abstract

Although the TNM system is the accepted standard for head and neck tumor classification, there are often discrepancies between tumor size and survival. This retrospective analysis of 89 patients with squamous cell carcinoma of the buccal mucosa was carried out to evaluate tumor thickness and depth of invasion as prognostic variables and to compare them to the standard parameters. Recurrence rates increased with tumor size, clinical stage, thickness, and depth of invasion. In univariate analysis, sex, clinical stage, thickness, and depth of invasion were significantly related to survival (p < 0.10). Multivariate analysis revealed that only thickness was an independent variable (p < 0.0001). Patients with tumors less than 6 mm in thickness had a significantly better survival rate compared with those patients with tumors greater than 6 mm in thickness, regardless of the tumor stage. Measurement of tumor thickness should be included in estimating prognosis, planning therapy, and comparing results in patients with squamous cell carcinoma of the buccal mucosa.

Original languageEnglish (US)
Pages (from-to)411-414
Number of pages4
JournalThe American Journal of Surgery
Volume154
Issue number4
DOIs
StatePublished - 1987
Externally publishedYes

Fingerprint

Mouth Mucosa
Squamous Cell Carcinoma
Neoplasms
Survival
Neck
Multivariate Analysis
Survival Rate
Head
Recurrence

ASJC Scopus subject areas

  • Surgery

Cite this

Squamous cell carcinoma of the buccal mucosa : Analysis of prognostic factors. / Urist, Marshall M.; O'Brien, Christopher J.; Soong, Seng Jaw; Visscher, Daniel W; Maddox, William A.

In: The American Journal of Surgery, Vol. 154, No. 4, 1987, p. 411-414.

Research output: Contribution to journalArticle

Urist, Marshall M. ; O'Brien, Christopher J. ; Soong, Seng Jaw ; Visscher, Daniel W ; Maddox, William A. / Squamous cell carcinoma of the buccal mucosa : Analysis of prognostic factors. In: The American Journal of Surgery. 1987 ; Vol. 154, No. 4. pp. 411-414.
@article{7e99c702f5114b11af85e32faafe8827,
title = "Squamous cell carcinoma of the buccal mucosa: Analysis of prognostic factors",
abstract = "Although the TNM system is the accepted standard for head and neck tumor classification, there are often discrepancies between tumor size and survival. This retrospective analysis of 89 patients with squamous cell carcinoma of the buccal mucosa was carried out to evaluate tumor thickness and depth of invasion as prognostic variables and to compare them to the standard parameters. Recurrence rates increased with tumor size, clinical stage, thickness, and depth of invasion. In univariate analysis, sex, clinical stage, thickness, and depth of invasion were significantly related to survival (p < 0.10). Multivariate analysis revealed that only thickness was an independent variable (p < 0.0001). Patients with tumors less than 6 mm in thickness had a significantly better survival rate compared with those patients with tumors greater than 6 mm in thickness, regardless of the tumor stage. Measurement of tumor thickness should be included in estimating prognosis, planning therapy, and comparing results in patients with squamous cell carcinoma of the buccal mucosa.",
author = "Urist, {Marshall M.} and O'Brien, {Christopher J.} and Soong, {Seng Jaw} and Visscher, {Daniel W} and Maddox, {William A.}",
year = "1987",
doi = "10.1016/0002-9610(89)90014-7",
language = "English (US)",
volume = "154",
pages = "411--414",
journal = "American Journal of Surgery",
issn = "0002-9610",
publisher = "Elsevier Inc.",
number = "4",

}

TY - JOUR

T1 - Squamous cell carcinoma of the buccal mucosa

T2 - Analysis of prognostic factors

AU - Urist, Marshall M.

AU - O'Brien, Christopher J.

AU - Soong, Seng Jaw

AU - Visscher, Daniel W

AU - Maddox, William A.

PY - 1987

Y1 - 1987

N2 - Although the TNM system is the accepted standard for head and neck tumor classification, there are often discrepancies between tumor size and survival. This retrospective analysis of 89 patients with squamous cell carcinoma of the buccal mucosa was carried out to evaluate tumor thickness and depth of invasion as prognostic variables and to compare them to the standard parameters. Recurrence rates increased with tumor size, clinical stage, thickness, and depth of invasion. In univariate analysis, sex, clinical stage, thickness, and depth of invasion were significantly related to survival (p < 0.10). Multivariate analysis revealed that only thickness was an independent variable (p < 0.0001). Patients with tumors less than 6 mm in thickness had a significantly better survival rate compared with those patients with tumors greater than 6 mm in thickness, regardless of the tumor stage. Measurement of tumor thickness should be included in estimating prognosis, planning therapy, and comparing results in patients with squamous cell carcinoma of the buccal mucosa.

AB - Although the TNM system is the accepted standard for head and neck tumor classification, there are often discrepancies between tumor size and survival. This retrospective analysis of 89 patients with squamous cell carcinoma of the buccal mucosa was carried out to evaluate tumor thickness and depth of invasion as prognostic variables and to compare them to the standard parameters. Recurrence rates increased with tumor size, clinical stage, thickness, and depth of invasion. In univariate analysis, sex, clinical stage, thickness, and depth of invasion were significantly related to survival (p < 0.10). Multivariate analysis revealed that only thickness was an independent variable (p < 0.0001). Patients with tumors less than 6 mm in thickness had a significantly better survival rate compared with those patients with tumors greater than 6 mm in thickness, regardless of the tumor stage. Measurement of tumor thickness should be included in estimating prognosis, planning therapy, and comparing results in patients with squamous cell carcinoma of the buccal mucosa.

UR - http://www.scopus.com/inward/record.url?scp=0023546219&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023546219&partnerID=8YFLogxK

U2 - 10.1016/0002-9610(89)90014-7

DO - 10.1016/0002-9610(89)90014-7

M3 - Article

C2 - 3661845

AN - SCOPUS:0023546219

VL - 154

SP - 411

EP - 414

JO - American Journal of Surgery

JF - American Journal of Surgery

SN - 0002-9610

IS - 4

ER -