Spontaneous thrombolysis of native artery occlusions

Kevin J. Ose, John Blebea, Richard J. Fowl, Richard F. Kempczinski

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Acute arterial ischemia of the lower extremities is a major cause of mortality and limb loss in patients with peripheral vascular disease. Patients with acute limb ischemia secondary to embolus or in situ thrombosis usually require emergency revascularization, either surgically or with the use of thrombolytic agents. It is commonly assumed that heparin therapy alone, without disobliterative intervention, can produce clinical improvement through continued patency and enlargement of the collateral circulation. The occurrence of spontaneous thrombolysis of major limb vessels is not generally accepted. We describe three patients, all with confirmed occlusion of either the iliac or superficial femoral arteries, who had spontaneous thrombolysis of occluded vessels. These experiences document that spontaneous resolution of arterial occlusion does occur, although it may be infrequent.

Original languageEnglish (US)
Pages (from-to)463-469
Number of pages7
JournalAnnals of Vascular Surgery
Volume7
Issue number5
DOIs
StatePublished - Sep 1993
Externally publishedYes

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Extremities
Arteries
Ischemia
Collateral Circulation
Fibrinolytic Agents
Peripheral Vascular Diseases
Femoral Artery
Embolism
Heparin
Lower Extremity
Emergencies
Thrombosis
Mortality
Therapeutics

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Ose, K. J., Blebea, J., Fowl, R. J., & Kempczinski, R. F. (1993). Spontaneous thrombolysis of native artery occlusions. Annals of Vascular Surgery, 7(5), 463-469. https://doi.org/10.1007/BF02002131

Spontaneous thrombolysis of native artery occlusions. / Ose, Kevin J.; Blebea, John; Fowl, Richard J.; Kempczinski, Richard F.

In: Annals of Vascular Surgery, Vol. 7, No. 5, 09.1993, p. 463-469.

Research output: Contribution to journalArticle

Ose, KJ, Blebea, J, Fowl, RJ & Kempczinski, RF 1993, 'Spontaneous thrombolysis of native artery occlusions', Annals of Vascular Surgery, vol. 7, no. 5, pp. 463-469. https://doi.org/10.1007/BF02002131
Ose, Kevin J. ; Blebea, John ; Fowl, Richard J. ; Kempczinski, Richard F. / Spontaneous thrombolysis of native artery occlusions. In: Annals of Vascular Surgery. 1993 ; Vol. 7, No. 5. pp. 463-469.
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