Spontaneous pneumomediastinum in a patient with bronchiolitis obliterans after bone marrow transplantation

E. Galanis; M. R. Litzow; A. Tefferi; J. P. Scott

doi:10.1038/sj.bmt.1700939

Spontaneous pneumomediastinum in a patient with bronchiolitis obliterans after bone marrow transplantation

E. Galanis, M. R. Litzow, A. Tefferi, J. P. Scott

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

After allogeneic bone marrow transplantation for chronic myelogenous leukemia, spontaneous pneumomediastinum and subcutaneous emphysema developed in a patient with bronchiolitis obliterans. Computed tomography scanning of the chest failed to reveal the cause. There was no evidence of a pulmonary process, pneumothorax, or pharyngeal or upper airway leak. Despite the alarming appearance of the patient, conservative management, including high-flow oxygen, resulted in resolution of the pneumomediastinum and subcutaneous emphysema. The cause of pneumomediastinum and subcutaneous emphysema in bone marrow transplant recipients is discussed.

Original language	English (US)
Pages (from-to)	695-696
Number of pages	2
Journal	Bone Marrow Transplantation
Volume	20
Issue number	8
DOIs	https://doi.org/10.1038/sj.bmt.1700939
State	Published - Oct 2 1997

Keywords

Bone marrow transplantation
Bronchiolitis obliterans
Graft-versus-host disease
Pneumomediastinum
Subcutaneous emphysema

ASJC Scopus subject areas

Hematology
Transplantation

Access to Document

10.1038/sj.bmt.1700939

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abstract = "After allogeneic bone marrow transplantation for chronic myelogenous leukemia, spontaneous pneumomediastinum and subcutaneous emphysema developed in a patient with bronchiolitis obliterans. Computed tomography scanning of the chest failed to reveal the cause. There was no evidence of a pulmonary process, pneumothorax, or pharyngeal or upper airway leak. Despite the alarming appearance of the patient, conservative management, including high-flow oxygen, resulted in resolution of the pneumomediastinum and subcutaneous emphysema. The cause of pneumomediastinum and subcutaneous emphysema in bone marrow transplant recipients is discussed.",

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