Splenectomy, Interferon, and Treatments of Historical Interest in Hairy Cell Leukemia

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10 Scopus citations

Abstract

The evolution and "lessons learned" for therapeutic options and approaches in HCL, which subsequently evolved into the adenosine deaminase inhibitors as the treatment of choice, has been intriguing [74-77]. The contributions to patient care and individual patient lives have been remarkable [78]. Observation, splenectomy, and recombinant interferon are potential therapeutic alternatives in select patients as initial therapy, and as therapeutic alternatives in the 10% of patients who have progressive disease after the purine nucleoside analogs.

Original languageEnglish (US)
Pages (from-to)1075-1086
Number of pages12
JournalHematology/Oncology Clinics of North America
Volume20
Issue number5
DOIs
StatePublished - Oct 1 2006

ASJC Scopus subject areas

  • Hematology
  • Oncology

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