Spinal metastases of extramammary paget disease with radiologic-pathologic correlation

Jason T. Little, Vance T. Lehman, Jonathan M. Morris, Julia S. Lehman, Felix E. Diehn

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Extramammary Paget disease (EMPD) is an uncommon malignancy. It manifests either in the primary form in the skin as an intraepithelial neoplasm, or in secondary form as pagetoid (intraepithelial) spread of an underlying internal carcinoma to the skin. Although local invasion and recurrence of primary extramammary Paget disease are relatively frequent, widespread metastases are rare. As such, there are very few reports and little characterization of the radiologic features of widespread spinal metastases. To our knowledge, there are no prior reports of a metastatic extramammary Paget disease presenting as a painful pathologic vertebral body compression fracture. We report the radiological features of a case of primary extramammary Paget disease with subsequent spinal metastases presenting as a painful compression fracture.

Original languageEnglish (US)
Pages (from-to)1-8
Number of pages8
JournalJournal of Radiology Case Reports
Volume10
Issue number5
DOIs
StatePublished - May 2016

Keywords

  • Extramammary Paget disease
  • Spinal metastases
  • Spine MRI

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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