Spinal cord and intradural-extraparenchymal spinal tumors: Current best care practices and strategies

Andrew T. Parsa, Janet Lee, Ian F. Parney, Philip Weinstein, Paul C. McCormick, Christopher Ames

Research output: Contribution to journalArticle

93 Scopus citations

Abstract

The management of patients with intradural spinal tumors differs in many respects from approaches taken for patients with intracranial tumors. Intramedullary lesions are often completely surrounded by normal spinal cord, displacing vital functional tracts eccentrically. Extramedullary lesions can drastically compress the spinal cord and nerve roots, reducing normal tissue to a ribbon-like consistency. The small amount of normal tissue relative to tumor has implications for surgery and postoperative adjuvant therapy. In addition, operative intervention must take spinal stability into consideration. In this report, we describe the current best care practices and strategies for patients with a diagnosis of spinal astrocytoma, ependymoma, hemangioblastoma, schwannoma, and meningioma. Treatment of patients with intradural tumors of the spinal cord and adjoining structures has changed over the past 20 years. Advances in many disciplines including neuroradiology, neurosurgery, neurooncology, and neuropathology have contributed to expediting diagnosis and improving outcomes.

Original languageEnglish (US)
Pages (from-to)291-318
Number of pages28
JournalJournal of neuro-oncology
Volume69
Issue number1-3
DOIs
StatePublished - Aug 1 2004

Keywords

  • Ependymoma
  • Hemangioblastoma
  • Meningioma
  • Schwannoma
  • Spinal astrocytoma

ASJC Scopus subject areas

  • Oncology
  • Neurology
  • Clinical Neurology
  • Cancer Research

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