Speech and language findings associated with paraneoplastic cerebellar degeneration

Teresa Paslawski, Joseph R. Duffy, Steven Vernino

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Paraneoplastic cerebellar degeneration (PCD) is an autoimmune disease that can be associated with cancer of the breast, lung, and ovary. The clinical presentation of PCD commonly includes ataxia, visual disturbances, and dysarthria. The speech disturbances associated with PCD have not been well characterized, despite general acceptance that dysarthria is often part of the initial presentation. A retrospective study was conducted of the speech, language, and swallowing concerns of patients with PCD evaluated at the Mayo Clinic in Rochester, MN, between 1990 and 2001. Prospective speech and language assessments were then conducted with 5 patients who had PCD. While ataxic dysarthria was the most common speech diagnosis, a spastic component was recognized frequently enough to suggest that the subacute (days to weeks) emergence and progression of an ataxic or mixed ataxic-spastic dysarthria in the setting of a more diffuse cerebellar ataxia should raise suspicions about PCD and justify further investigation of a possible immune-related etiology.

Original languageEnglish (US)
Pages (from-to)200-207
Number of pages8
JournalAmerican Journal of Speech-Language Pathology
Volume14
Issue number3
DOIs
StatePublished - Aug 2005

Fingerprint

Paraneoplastic Cerebellar Degeneration
Dysarthria
Language
physical disability
language
etiology
Cerebellar Ataxia
cancer
Muscle Spasticity
acceptance
Ataxia
Deglutition
Disease
Ovarian Neoplasms
Autoimmune Diseases
Lung Neoplasms
Retrospective Studies
Breast Neoplasms

Keywords

  • Ataxia
  • Brain disorders
  • Cerebellum
  • Dysarthria

ASJC Scopus subject areas

  • Rehabilitation
  • Health Professions(all)
  • Linguistics and Language

Cite this

Speech and language findings associated with paraneoplastic cerebellar degeneration. / Paslawski, Teresa; Duffy, Joseph R.; Vernino, Steven.

In: American Journal of Speech-Language Pathology, Vol. 14, No. 3, 08.2005, p. 200-207.

Research output: Contribution to journalArticle

Paslawski, Teresa ; Duffy, Joseph R. ; Vernino, Steven. / Speech and language findings associated with paraneoplastic cerebellar degeneration. In: American Journal of Speech-Language Pathology. 2005 ; Vol. 14, No. 3. pp. 200-207.
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