Spectrum of pulmonary neuroendocrine cell proliferation: Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia, tumorlet, and carcinoids

Chi Wan Koo, Jeffrey P. Baliff, Drew A. Torigian, Leslie A. Litzky, Warren B. Gefter, Scott R. Akers

Research output: Contribution to journalArticle

30 Scopus citations

Abstract

OBJECTIVE. The objectives of this article are to review the radiologic, pathologic, and clinical features of diffuse idiopathic pulmonary neuroendocrine cell hyperplasia, tumorlet, and carcinoids and to discuss the possible role of diffuse idiopathic pulmonary neuroendocrine cell hyperplasia and tumorlet in the development of carcinoids. CONCLUSION. Given the potential significant morbidity of diffuse idiopathic pulmonary neuroendocrine cell hyperplasia and its neoplastic counterparts, it is important to understand and recognize these disease entities. A conceptual continuum of these neuroendocrine entities is suggested.

Original languageEnglish (US)
Pages (from-to)661-668
Number of pages8
JournalAmerican Journal of Roentgenology
Volume195
Issue number3
DOIs
StatePublished - Sep 1 2010

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Keywords

  • Carcinoids
  • Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia
  • Lung neoplasms
  • Oncologic imaging
  • Tumorlet

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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