Spectral resolution enhancement by chemical shift imaging

Igor Serša, Slobodan Macura

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Three-dimensional chemical shift imaging (3D CSI) with appropriate data postprocessing can be used as a tool to improve spectral resolution in samples where large susceptibility differences and limited shim capabilities prevent good sample shimming. Data postprocessing is reduced to the realignment of individual 3D voxel spectra. As a result, the line broadening due to the field inhomogeneity over the sample's volume is reduced to the broadening by inhomogeneity within individual voxels. We compared this method with the resolution enhancement by window multiplication. We demonstrated, theoretically and experimentally, that in the presence of large, lower-order gradients, 3D CSI achieves better resolution enhancement with smaller sensitivity losses. An application of the method to a simple biological system is presented as well.

Original languageEnglish (US)
Pages (from-to)250-258
Number of pages9
JournalMagnetic Resonance Imaging
Volume25
Issue number2
DOIs
StatePublished - Feb 2007

Keywords

  • Chemical shift imaging
  • Magnetic field inhomogeneity
  • Resolution-enhancement filtering
  • Signal-to-noise ratio
  • Spectroscopic resolution

ASJC Scopus subject areas

  • Biophysics
  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging

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