Spectral analysis of heart sounds associated with coronary occlusions

Dominique Gauthier; Yasemin M. Akay; Robert G. Paden; William Pavliecek; F. David Fortuin; John K. Sweeney; Richard W. Lee; Metin Akay

doi:10.1109/ITAB.2007.4407421

Spectral analysis of heart sounds associated with coronary occlusions

Dominique Gauthier, Yasemin M. Akay, Robert G. Paden, William Pavliecek, F. David Fortuin, John K. Sweeney, Richard W. Lee, Metin Akay

Cardiovascular Diseases

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

27 Scopus citations

Abstract

Numerous studies based on the spectral analysis of diastolic sounds showed an increase in the high frequency portion of the spectrum for patients with coronary artery disease (CAD) compared with normal patients. The overall goal of this study is to detect the presence of coronary artery disease in patients using a noninvasive and inexpensive approach. A commercially available electronic stethoscope was used to record the diastolic heart sounds from patients diagnosed with or without CAD based on their coronary angiography examination. The Fast Fourier Transform, a widely used signal processing method, was then implemented on the diastolic segments. The power ratios of the energy above 130 Hz to the energy below 130 Hz were calculated for normal and abnormal patients and compared. Results furthermore confirmed that patients with CAD have more energy in the higher portion of their spectrum, resulting in higher power ratios than for normal patients (p < 0.05). This approach led to a sensitivity of 71%, a specificity of 83% and an overall accuracy of 73.3% using an optimal threshold ratio of 1.5. These results suggest that the proposed system could be used in clinics as part of standard physical examinations.

Original language	English (US)
Title of host publication	6th International Special Topic Conference on ITAB, 2007
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	49-52
Number of pages	4
ISBN (Print)	9781424418688
DOIs	https://doi.org/10.1109/ITAB.2007.4407421
State	Published - Jan 1 2007
Event	6th International Special Topic Conference on ITAB, 2007 - Tokyo, Japan Duration: Nov 8 2007 → Nov 11 2007

Publication series

Name	Proceedings of the IEEE/EMBS Region 8 International Conference on Information Technology Applications in Biomedicine, ITAB

Other

Other	6th International Special Topic Conference on ITAB, 2007
Country/Territory	Japan
City	Tokyo
Period	11/8/07 → 11/11/07

Keywords

Coronary artery disease
Fast Fourier Transform
Occlusions
Power ratio
Spectral energy

ASJC Scopus subject areas

General Engineering
General Computer Science

Access to Document

10.1109/ITAB.2007.4407421

Cite this

Gauthier, D., Akay, Y. M., Paden, R. G., Pavliecek, W., Fortuin, F. D., Sweeney, J. K., Lee, R. W., & Akay, M. (2007). Spectral analysis of heart sounds associated with coronary occlusions. In 6th International Special Topic Conference on ITAB, 2007 (pp. 49-52). Article 4407421 (Proceedings of the IEEE/EMBS Region 8 International Conference on Information Technology Applications in Biomedicine, ITAB). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/ITAB.2007.4407421

Spectral analysis of heart sounds associated with coronary occlusions. / Gauthier, Dominique; Akay, Yasemin M.; Paden, Robert G. et al.
6th International Special Topic Conference on ITAB, 2007. Institute of Electrical and Electronics Engineers Inc., 2007. p. 49-52 4407421 (Proceedings of the IEEE/EMBS Region 8 International Conference on Information Technology Applications in Biomedicine, ITAB).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Gauthier, D, Akay, YM, Paden, RG, Pavliecek, W, Fortuin, FD, Sweeney, JK, Lee, RW & Akay, M 2007, Spectral analysis of heart sounds associated with coronary occlusions. in 6th International Special Topic Conference on ITAB, 2007., 4407421, Proceedings of the IEEE/EMBS Region 8 International Conference on Information Technology Applications in Biomedicine, ITAB, Institute of Electrical and Electronics Engineers Inc., pp. 49-52, 6th International Special Topic Conference on ITAB, 2007, Tokyo, Japan, 11/8/07. https://doi.org/10.1109/ITAB.2007.4407421

Gauthier D, Akay YM, Paden RG, Pavliecek W, Fortuin FD, Sweeney JK et al. Spectral analysis of heart sounds associated with coronary occlusions. In 6th International Special Topic Conference on ITAB, 2007. Institute of Electrical and Electronics Engineers Inc. 2007. p. 49-52. 4407421. (Proceedings of the IEEE/EMBS Region 8 International Conference on Information Technology Applications in Biomedicine, ITAB). doi: 10.1109/ITAB.2007.4407421

Gauthier, Dominique ; Akay, Yasemin M. ; Paden, Robert G. et al. / Spectral analysis of heart sounds associated with coronary occlusions. 6th International Special Topic Conference on ITAB, 2007. Institute of Electrical and Electronics Engineers Inc., 2007. pp. 49-52 (Proceedings of the IEEE/EMBS Region 8 International Conference on Information Technology Applications in Biomedicine, ITAB).

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abstract = "Numerous studies based on the spectral analysis of diastolic sounds showed an increase in the high frequency portion of the spectrum for patients with coronary artery disease (CAD) compared with normal patients. The overall goal of this study is to detect the presence of coronary artery disease in patients using a noninvasive and inexpensive approach. A commercially available electronic stethoscope was used to record the diastolic heart sounds from patients diagnosed with or without CAD based on their coronary angiography examination. The Fast Fourier Transform, a widely used signal processing method, was then implemented on the diastolic segments. The power ratios of the energy above 130 Hz to the energy below 130 Hz were calculated for normal and abnormal patients and compared. Results furthermore confirmed that patients with CAD have more energy in the higher portion of their spectrum, resulting in higher power ratios than for normal patients (p < 0.05). This approach led to a sensitivity of 71%, a specificity of 83% and an overall accuracy of 73.3% using an optimal threshold ratio of 1.5. These results suggest that the proposed system could be used in clinics as part of standard physical examinations.",

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AB - Numerous studies based on the spectral analysis of diastolic sounds showed an increase in the high frequency portion of the spectrum for patients with coronary artery disease (CAD) compared with normal patients. The overall goal of this study is to detect the presence of coronary artery disease in patients using a noninvasive and inexpensive approach. A commercially available electronic stethoscope was used to record the diastolic heart sounds from patients diagnosed with or without CAD based on their coronary angiography examination. The Fast Fourier Transform, a widely used signal processing method, was then implemented on the diastolic segments. The power ratios of the energy above 130 Hz to the energy below 130 Hz were calculated for normal and abnormal patients and compared. Results furthermore confirmed that patients with CAD have more energy in the higher portion of their spectrum, resulting in higher power ratios than for normal patients (p < 0.05). This approach led to a sensitivity of 71%, a specificity of 83% and an overall accuracy of 73.3% using an optimal threshold ratio of 1.5. These results suggest that the proposed system could be used in clinics as part of standard physical examinations.

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Spectral analysis of heart sounds associated with coronary occlusions

Abstract

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Keywords

ASJC Scopus subject areas

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