Species of Propionibacterium and Propionibacterium acnes phylotypes associated with orthopedic implants

Marta Fernandez Sampedro, Kerryl E. Piper, Andrew McDowell, Sheila Patrick, Jayawant Mandrekar, Mark S. Rouse, James M. Steckelberg, Robin Patel

Research output: Contribution to journalArticle

55 Citations (Scopus)

Abstract

Propionibacterium sp. is commonly isolated in association with orthopedic implants, either as a pathogen or a colonizer. Microbial characteristics that indicate whether the isolated species is a likely cause of orthopedic implant infection versus a colonizing agent would be clinically useful. We performed a prospective trial to determine the species of Propionibacterium and the phylotype (IA, IB, II, III) of Propionibacterium acnes isolated from the surface of removed orthopedic implants, and we correlated these findings with the presence or absence of infection. P. acnes represented 61 of 62 isolates. P. acnes type I was more commonly isolated than was type II (62% versus 38%, respectively), whether associated with infection or not. P. acnes type III was not detected. There was no clear association between types I and II P. acnes and infection or colonization of failed orthopedic implants (P = 0.75), however type IB strains were more frequently isolated than type IA from infected prosthese.

Original languageEnglish (US)
Pages (from-to)138-145
Number of pages8
JournalDiagnostic Microbiology and Infectious Disease
Volume64
Issue number2
DOIs
StatePublished - Jun 2009
Externally publishedYes

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Propionibacterium
Propionibacterium acnes
Orthopedics
Infection

Keywords

  • orthopedic implants
  • Propionibacterium acnes
  • Propionibacterium spp.

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Cite this

Species of Propionibacterium and Propionibacterium acnes phylotypes associated with orthopedic implants. / Fernandez Sampedro, Marta; Piper, Kerryl E.; McDowell, Andrew; Patrick, Sheila; Mandrekar, Jayawant; Rouse, Mark S.; Steckelberg, James M.; Patel, Robin.

In: Diagnostic Microbiology and Infectious Disease, Vol. 64, No. 2, 06.2009, p. 138-145.

Research output: Contribution to journalArticle

Fernandez Sampedro, Marta ; Piper, Kerryl E. ; McDowell, Andrew ; Patrick, Sheila ; Mandrekar, Jayawant ; Rouse, Mark S. ; Steckelberg, James M. ; Patel, Robin. / Species of Propionibacterium and Propionibacterium acnes phylotypes associated with orthopedic implants. In: Diagnostic Microbiology and Infectious Disease. 2009 ; Vol. 64, No. 2. pp. 138-145.
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