Spanish- and English-Speaking Pregnant Women’s Views on cfDNA and Other Prenatal Screening

Practical and Ethical Reflections

Erin Floyd, Megan Allyse, Marsha Michie

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The rapid clinical implementation of cell-free DNA (cfDNA) screening, a non-invasive method of prenatal genetic screening, has outpaced research on its social and ethical implications. This study is the first to compare the ethical and practical views of Spanish- and English-speaking pregnant women in the United States about cfDNA screening. Semi-structured interviews were conducted with diverse Spanish- and English-speaking women who had received prenatal care at a large academic medical center. Of the 24 interviewees, ten were Latinas who were interviewed in Spanish; English-language interviews were conducted with seven non-Hispanic Asian and seven non-Hispanic White women. Participants held positive opinions concerning the accuracy of cfDNA screening and often noted that it would enhance preparedness. Participants also expressed concerns about the possibility of inaccurate results and the potentially negative effects of cfDNA screening on the experience of pregnancy. Differences emerged between Spanish and English speakers in their portrayals of their relationships with prenatal health care providers, the extent to which they questioned providers’ advice, their ethical concerns, and their informational needs. We emphasize the importance of customizing prenatal test counseling to the needs of the individual patient, providing educationally appropriate counseling and literature, and mitigating potential language barriers.

Original languageEnglish (US)
Pages (from-to)965-977
Number of pages13
JournalJournal of Genetic Counseling
Volume25
Issue number5
DOIs
StatePublished - Oct 1 2016

Fingerprint

Prenatal Diagnosis
Pregnant Women
Prenatal Care
DNA
Counseling
Interviews
Communication Barriers
Genetic Testing
Hispanic Americans
Health Personnel
Language
Pregnancy
Research

Keywords

  • cfDNA
  • cfDNA screening
  • Ethics
  • Latinas
  • NIPS
  • NIPT
  • Prenatal screening
  • Spanish-speakers

ASJC Scopus subject areas

  • Genetics(clinical)

Cite this

Spanish- and English-Speaking Pregnant Women’s Views on cfDNA and Other Prenatal Screening : Practical and Ethical Reflections. / Floyd, Erin; Allyse, Megan; Michie, Marsha.

In: Journal of Genetic Counseling, Vol. 25, No. 5, 01.10.2016, p. 965-977.

Research output: Contribution to journalArticle

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