SOX2 Determines Lineage Restriction: Modeling Lung Squamous Cell Carcinoma in the Mouse

Nicole R. Murray; Verline Justilien; Alan P. Fields

doi:10.1016/j.ccell.2016.09.012

SOX2 Determines Lineage Restriction: Modeling Lung Squamous Cell Carcinoma in the Mouse

Nicole R. Murray, Verline Justilien, Alan P. Fields

Cancer Biology

Research output: Contribution to journal › Short survey › peer-review

8 Scopus citations

Abstract

In this issue of Cancer Cell, Ferone et al. demonstrate that SOX2 not only drives lung tumor formation but also restricts tumor lineage to squamous cell carcinoma (LSCC), regardless of cell of origin. This novel LSCC model should facilitate identification of key oncogenic drivers and treatment strategies for this lung cancer subtype.

Original language	English (US)
Pages (from-to)	505-507
Number of pages	3
Journal	Cancer cell
Volume	30
Issue number	4
DOIs	https://doi.org/10.1016/j.ccell.2016.09.012
State	Published - Oct 10 2016

ASJC Scopus subject areas

Oncology
Cell Biology
Cancer Research

Access to Document

10.1016/j.ccell.2016.09.012

Cite this

@article{7e0fc38287fe48a0be2df794fdba33b5,

title = "SOX2 Determines Lineage Restriction: Modeling Lung Squamous Cell Carcinoma in the Mouse",

abstract = "In this issue of Cancer Cell, Ferone et al. demonstrate that SOX2 not only drives lung tumor formation but also restricts tumor lineage to squamous cell carcinoma (LSCC), regardless of cell of origin. This novel LSCC model should facilitate identification of key oncogenic drivers and treatment strategies for this lung cancer subtype.",

author = "Murray, {Nicole R.} and Verline Justilien and Fields, {Alan P.}",

note = "Publisher Copyright: {\textcopyright} 2016 Elsevier Inc.",

year = "2016",

month = oct,

day = "10",

doi = "10.1016/j.ccell.2016.09.012",

language = "English (US)",

volume = "30",

pages = "505--507",

journal = "Cancer cell",

issn = "1535-6108",

publisher = "Cell Press",

number = "4",

}

TY - JOUR

T1 - SOX2 Determines Lineage Restriction

T2 - Modeling Lung Squamous Cell Carcinoma in the Mouse

AU - Murray, Nicole R.

AU - Justilien, Verline

AU - Fields, Alan P.

PY - 2016/10/10

Y1 - 2016/10/10

N2 - In this issue of Cancer Cell, Ferone et al. demonstrate that SOX2 not only drives lung tumor formation but also restricts tumor lineage to squamous cell carcinoma (LSCC), regardless of cell of origin. This novel LSCC model should facilitate identification of key oncogenic drivers and treatment strategies for this lung cancer subtype.

AB - In this issue of Cancer Cell, Ferone et al. demonstrate that SOX2 not only drives lung tumor formation but also restricts tumor lineage to squamous cell carcinoma (LSCC), regardless of cell of origin. This novel LSCC model should facilitate identification of key oncogenic drivers and treatment strategies for this lung cancer subtype.

UR - http://www.scopus.com/inward/record.url?scp=84991813369&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84991813369&partnerID=8YFLogxK

U2 - 10.1016/j.ccell.2016.09.012

DO - 10.1016/j.ccell.2016.09.012

M3 - Short survey

C2 - 27728797

AN - SCOPUS:84991813369

SN - 1535-6108

VL - 30

SP - 505

EP - 507

JO - Cancer cell

JF - Cancer cell

IS - 4

ER -

SOX2 Determines Lineage Restriction: Modeling Lung Squamous Cell Carcinoma in the Mouse

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this