Integrative neuroendocrine control of the gonadotropic and somatotropic axes in childhood, puberty, and young adulthood proceeds via multiple convergent and divergent pathways in the human and experimental animal. Emerging ensemble concepts are required to embody independent, parallel, and interacting mechanisms that subserve physiological adaptations and pathological disruption of reproduction and growth. Significant advances in systems biology will be needed to address these challenges.
|Original language||English (US)|
|Number of pages||40|
|State||Published - Apr 2006|
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism