Smoking and acute urinary retention

The Olmsted County study of urinary symptoms and health status among men

Aruna V. Sarma, Debra J. Jacobson, Jennifer St. Sauver, Michael M. Lieber, Cynthia J. Girman, Ajay Nehra, Steven J. Jacobsen

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

BACKGROUND. Previous reports have suggested an inverse relationship between smoking and surgery for benign prostatic hyperplasia (BPH). We hypothesized that acute urinary retention (AUR), an adverse outcome of this disease and indication for surgical treatment, may be related to smoking. METHODS. Study subjects were randomly selected from Olmsted County men aged 40-79 identified through the Rochester Epidemiology Project. Of the 3,854 eligible men, 2,089 (54%) completed a questionnaire that included the American Urological Association Symptom Score and assessed smoking status. Community medical records were examined for occurrence of AUR with documented catheterization in the subsequent 10 years and occurrence of BPH surgery. Proportional hazard models were used to assess the relationship between baseline smoking status and subsequent retention. RESULTS. In the 18,307 person-years of follow-up, 114 men had AUR. When compared to 727 never-smokers, there was a trend among the 336 current smokers to be at lower risk (Relative risk (RR) = 0.62, 95% Confidence Interval (CI) = 0.33, 1.18) whereas the 1,026 former smokers were at similar risk to non-smokers (RR = 1.0, 95%CI = 0.67, 1.46). Among men with moderate-severe symptoms at baseline, current smokers were at lower risk of retention compared to non-smokers (RR = 0.65, 95%CI = 0.22, 1.91) but the association approached the null among those with none-mild symptoms (RR = 0.91, 95% CI = 0.40, 2.06). CONCLUSIONS. Community-dwelling men who currently smoke may be at a modestly reduced risk of AUR. The magnitude of this association is sufficiently small that it seems unlikely that this explains a sizable proportion of the inverse association between smoking and surgically treated BPH.

Original languageEnglish (US)
Pages (from-to)699-705
Number of pages7
JournalProstate
Volume69
Issue number7
DOIs
StatePublished - May 15 2009

Fingerprint

Urinary Retention
Health Status
Smoking
Prostatic Hyperplasia
Confidence Intervals
Independent Living
Proportional Hazards Models
Smoke
Catheterization
Medical Records
Epidemiology

Keywords

  • Acute urinary retention
  • Aging
  • BPH
  • Men
  • Smoking

ASJC Scopus subject areas

  • Urology
  • Oncology
  • Medicine(all)

Cite this

Sarma, A. V., Jacobson, D. J., St. Sauver, J., Lieber, M. M., Girman, C. J., Nehra, A., & Jacobsen, S. J. (2009). Smoking and acute urinary retention: The Olmsted County study of urinary symptoms and health status among men. Prostate, 69(7), 699-705. https://doi.org/10.1002/pros.20914

Smoking and acute urinary retention : The Olmsted County study of urinary symptoms and health status among men. / Sarma, Aruna V.; Jacobson, Debra J.; St. Sauver, Jennifer; Lieber, Michael M.; Girman, Cynthia J.; Nehra, Ajay; Jacobsen, Steven J.

In: Prostate, Vol. 69, No. 7, 15.05.2009, p. 699-705.

Research output: Contribution to journalArticle

Sarma, AV, Jacobson, DJ, St. Sauver, J, Lieber, MM, Girman, CJ, Nehra, A & Jacobsen, SJ 2009, 'Smoking and acute urinary retention: The Olmsted County study of urinary symptoms and health status among men', Prostate, vol. 69, no. 7, pp. 699-705. https://doi.org/10.1002/pros.20914
Sarma, Aruna V. ; Jacobson, Debra J. ; St. Sauver, Jennifer ; Lieber, Michael M. ; Girman, Cynthia J. ; Nehra, Ajay ; Jacobsen, Steven J. / Smoking and acute urinary retention : The Olmsted County study of urinary symptoms and health status among men. In: Prostate. 2009 ; Vol. 69, No. 7. pp. 699-705.
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abstract = "BACKGROUND. Previous reports have suggested an inverse relationship between smoking and surgery for benign prostatic hyperplasia (BPH). We hypothesized that acute urinary retention (AUR), an adverse outcome of this disease and indication for surgical treatment, may be related to smoking. METHODS. Study subjects were randomly selected from Olmsted County men aged 40-79 identified through the Rochester Epidemiology Project. Of the 3,854 eligible men, 2,089 (54{\%}) completed a questionnaire that included the American Urological Association Symptom Score and assessed smoking status. Community medical records were examined for occurrence of AUR with documented catheterization in the subsequent 10 years and occurrence of BPH surgery. Proportional hazard models were used to assess the relationship between baseline smoking status and subsequent retention. RESULTS. In the 18,307 person-years of follow-up, 114 men had AUR. When compared to 727 never-smokers, there was a trend among the 336 current smokers to be at lower risk (Relative risk (RR) = 0.62, 95{\%} Confidence Interval (CI) = 0.33, 1.18) whereas the 1,026 former smokers were at similar risk to non-smokers (RR = 1.0, 95{\%}CI = 0.67, 1.46). Among men with moderate-severe symptoms at baseline, current smokers were at lower risk of retention compared to non-smokers (RR = 0.65, 95{\%}CI = 0.22, 1.91) but the association approached the null among those with none-mild symptoms (RR = 0.91, 95{\%} CI = 0.40, 2.06). CONCLUSIONS. Community-dwelling men who currently smoke may be at a modestly reduced risk of AUR. The magnitude of this association is sufficiently small that it seems unlikely that this explains a sizable proportion of the inverse association between smoking and surgically treated BPH.",
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AU - Sarma, Aruna V.

AU - Jacobson, Debra J.

AU - St. Sauver, Jennifer

AU - Lieber, Michael M.

AU - Girman, Cynthia J.

AU - Nehra, Ajay

AU - Jacobsen, Steven J.

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N2 - BACKGROUND. Previous reports have suggested an inverse relationship between smoking and surgery for benign prostatic hyperplasia (BPH). We hypothesized that acute urinary retention (AUR), an adverse outcome of this disease and indication for surgical treatment, may be related to smoking. METHODS. Study subjects were randomly selected from Olmsted County men aged 40-79 identified through the Rochester Epidemiology Project. Of the 3,854 eligible men, 2,089 (54%) completed a questionnaire that included the American Urological Association Symptom Score and assessed smoking status. Community medical records were examined for occurrence of AUR with documented catheterization in the subsequent 10 years and occurrence of BPH surgery. Proportional hazard models were used to assess the relationship between baseline smoking status and subsequent retention. RESULTS. In the 18,307 person-years of follow-up, 114 men had AUR. When compared to 727 never-smokers, there was a trend among the 336 current smokers to be at lower risk (Relative risk (RR) = 0.62, 95% Confidence Interval (CI) = 0.33, 1.18) whereas the 1,026 former smokers were at similar risk to non-smokers (RR = 1.0, 95%CI = 0.67, 1.46). Among men with moderate-severe symptoms at baseline, current smokers were at lower risk of retention compared to non-smokers (RR = 0.65, 95%CI = 0.22, 1.91) but the association approached the null among those with none-mild symptoms (RR = 0.91, 95% CI = 0.40, 2.06). CONCLUSIONS. Community-dwelling men who currently smoke may be at a modestly reduced risk of AUR. The magnitude of this association is sufficiently small that it seems unlikely that this explains a sizable proportion of the inverse association between smoking and surgically treated BPH.

AB - BACKGROUND. Previous reports have suggested an inverse relationship between smoking and surgery for benign prostatic hyperplasia (BPH). We hypothesized that acute urinary retention (AUR), an adverse outcome of this disease and indication for surgical treatment, may be related to smoking. METHODS. Study subjects were randomly selected from Olmsted County men aged 40-79 identified through the Rochester Epidemiology Project. Of the 3,854 eligible men, 2,089 (54%) completed a questionnaire that included the American Urological Association Symptom Score and assessed smoking status. Community medical records were examined for occurrence of AUR with documented catheterization in the subsequent 10 years and occurrence of BPH surgery. Proportional hazard models were used to assess the relationship between baseline smoking status and subsequent retention. RESULTS. In the 18,307 person-years of follow-up, 114 men had AUR. When compared to 727 never-smokers, there was a trend among the 336 current smokers to be at lower risk (Relative risk (RR) = 0.62, 95% Confidence Interval (CI) = 0.33, 1.18) whereas the 1,026 former smokers were at similar risk to non-smokers (RR = 1.0, 95%CI = 0.67, 1.46). Among men with moderate-severe symptoms at baseline, current smokers were at lower risk of retention compared to non-smokers (RR = 0.65, 95%CI = 0.22, 1.91) but the association approached the null among those with none-mild symptoms (RR = 0.91, 95% CI = 0.40, 2.06). CONCLUSIONS. Community-dwelling men who currently smoke may be at a modestly reduced risk of AUR. The magnitude of this association is sufficiently small that it seems unlikely that this explains a sizable proportion of the inverse association between smoking and surgically treated BPH.

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