Small lesions in the heart identified at electron beam CT: Calcification or noise?

Lawrence F. Bielak, Rachel B. Kaufmann, Patricia P. Moll, Cynthia H McCollough, Robert S. Schwartz, Patrick F. Sheedy

Research output: Contribution to journalArticle

155 Citations (Scopus)

Abstract

PURPOSE: To identify a minimum definition of coronary artery calcification (CAC) at electron beam computed tomography (CT) that would give repeatable results and be accurate as a marker for coronary artery disease. MATERIALS AND METHODS: Hyperattenuating (>130 HU) foci 0.69-3.09 mm2 in area were evaluated for 256 subjects who underwent two sequential electron beam CT examinations to determine the percentage of hyperattenuating foci seen on a first examination that were seen again on a second examination. Accuracies of varying minimum definitions of CAC were determined in 160 subjects who underwent electron beam CT and coronary arteriography. RESULTS: Hyperattenuating foci more than 2 mm2 in area were seen again at a second examination in more than 50% of cases (P < .0001). At this minimum definition of CAC, the sensitivity and specificity for identifying any angiographically defined coronary artery disease were 82% and 85%, respectively. CONCLUSION: The 2-mm2-area definition of CAC was reliable and provided an accurate indication of coronary artery disease.

Original languageEnglish (US)
Pages (from-to)631-636
Number of pages6
JournalRadiology
Volume192
Issue number3
StatePublished - Sep 1994

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X Ray Computed Tomography
Noise
Coronary Vessels
Coronary Artery Disease
Angiography
Sensitivity and Specificity

Keywords

  • Coronary vessels, calcification
  • Coronary vessels, CT
  • Coronary vessels, stenosis or obstruction

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Bielak, L. F., Kaufmann, R. B., Moll, P. P., McCollough, C. H., Schwartz, R. S., & Sheedy, P. F. (1994). Small lesions in the heart identified at electron beam CT: Calcification or noise? Radiology, 192(3), 631-636.

Small lesions in the heart identified at electron beam CT : Calcification or noise? / Bielak, Lawrence F.; Kaufmann, Rachel B.; Moll, Patricia P.; McCollough, Cynthia H; Schwartz, Robert S.; Sheedy, Patrick F.

In: Radiology, Vol. 192, No. 3, 09.1994, p. 631-636.

Research output: Contribution to journalArticle

Bielak, LF, Kaufmann, RB, Moll, PP, McCollough, CH, Schwartz, RS & Sheedy, PF 1994, 'Small lesions in the heart identified at electron beam CT: Calcification or noise?', Radiology, vol. 192, no. 3, pp. 631-636.
Bielak LF, Kaufmann RB, Moll PP, McCollough CH, Schwartz RS, Sheedy PF. Small lesions in the heart identified at electron beam CT: Calcification or noise? Radiology. 1994 Sep;192(3):631-636.
Bielak, Lawrence F. ; Kaufmann, Rachel B. ; Moll, Patricia P. ; McCollough, Cynthia H ; Schwartz, Robert S. ; Sheedy, Patrick F. / Small lesions in the heart identified at electron beam CT : Calcification or noise?. In: Radiology. 1994 ; Vol. 192, No. 3. pp. 631-636.
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AU - Schwartz, Robert S.

AU - Sheedy, Patrick F.

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